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View Structure Prediction Details

Protein: bpl-1
Organism: Caenorhabditis elegans
Length: 558 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bpl-1.

Description E-value Query
Range
Subject
Range
CE31785 - WBGene00000259 locus:bpl-1 status:Partially_confirmed TR:Q9BI98 protein_id:AAK31491.2
477.0 [0..1] [558..494]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCKPNSVLVY TGGNDSLYSD IRHRLSFLLP PDEITVFNVS IQALKKQPWA EKSTVCVILA  60
   61 STNDLDDEAW EKIQAYFNQN GKIIFVCQNK LLASITGCDS SKANASILRF AFGSQN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKLKDTNKEF VKFLEKNMKK LPKSTAINET FRSKDVSVGA NFTVVLKKEP DAPLFLYMQN  60
   61 NGSLHASALF SDATTQQLIA PNSNLLKDSL RSVG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNVCDTTMPP LTKGILIAEY DSIIESIAGL RLGEEIGLQP RILLRKSDVV EELGLPEATE  60
   61 KLLPIEVVNR DSDAGTSKNF DFNLYFEQIH SKIGQVVLLV DVATTTMDII ESVNAGIPSL 120
  121 ESVVVIANRQ ISGRGRGGNE FLCPRGMAMF NFSFSISKKS RIAKHLPILQ HIFCVALVEA 180
  181 ARNLSGYPEF PLHIKWPNDL YCERSHKVGG MLLQCSTRDD SFRVSIGCGM NVSNDKPTMC 240
  241 LNDMLPKEAE TRITKEQLIA ETINKFTYYM KDYEDNGPET FKKKYHEYWL HSQQEVLLSD 300
  301 FNERVTIRGI DDDGYLQVRS KSNPDKIFSI GDDGNTFDMM KGLIRHKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.39794
Match: 1biaA
Description: THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 3.03334029653525 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.03334029653525 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 3.0330284950777 bayes_pls_golite062009
ligase activity 2.57747899218361 bayes_pls_golite062009
catalytic activity 2.36416267096403 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle