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Protein Overview: hgrs-1

General Information:
Name(s) found: hgrs-1 / CE32574 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00004101 locus:hgrs-1 status:Confirmed UniProt:Q17796 protein_id:CCD61398.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 729 amino acids

    Gene Ontology:
    Cellular Component: early endosome [IDALink to PubMed article]
    endosome membrane [IDALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    phosphatidylinositol-3-phosphate binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKFQRVLD QATDSTLVEP NWEGIILCTD MIRSGEVPAK PSLQAIRKRM QHENPHVVNH  60
   61 TLLVLDACVK NCGHKVHAEV ATREFMEDFK NLVTENKYDE VKNKSLEMLQ CWATAFANKP 120
  121 EYKMVVDTHN LMKLAGFDFP SLKEADAMFM AQVAPEWADG PECYRCRSVF SVFTRKHHCR 180
  181 ACGQIFCDKC SSRELALPQF GIEKEVRVCE TCYEKKVAEV KERYPAVKKQ LDAAHGRKGD 240
  241 SEADKAAKEK LLREKEEEDL ALAIAISQSE AEAKEKEKQN NLYSMYNGIK PEVDGYKGAA 300
  301 EPVTAPPPDD SSSDPLARYL NRDYWQQKKE GKVEDWSSRS SALSATAPPP SEPSIAPSIC 360
  361 STLMGPDDNS LNADIAAMSL GGTNGLNGTV SDDAKLQADD TMKWCQSIRE QVSVMDNRIR 420
  421 SNLARGRPVF NDSAIQDLFT KLTELHSHVL SRMHTLDEQR GYYESLQDHL ANIGEARQAI 480
  481 DEMREEHERK RQERMAEEQR LRQAQMQQTL EMMRMKKHAM LMEQREQALQ RFQQQQQEMA 540
  541 MRRHQQQAYY NPQQMGYGAP PPSGPQQPPQ QSYYGYQQGP QSQAPPPSSQ YQQSHASTQQ 600
  601 QQQQYYQHYQ ANQTVTQPVQ QAQQQYQQQY QGYYQQQQPY QQQAGYQNPQ QHQNYQNGTT 660
  661 NENGQYQQQQ SSEVKQEHQN HGYQQQQAQH PPASVASNGH NGYGNVDQNA HHHQQQQPQI 720
  721 AEQPLISFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..208] PSI-BLAST 81.30103 Hrs
    2 View Details [209..275] PSI-BLAST 4.39794 Crystal Structure of a FYVE-type domain from caspase regulator CARP2
    3 View Details [276..563] FFAS03 1.01 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    4 View Details [564..729] PSI-BLAST 7.221849 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.24093737575291 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  0.166244039424217 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle