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View Structure Prediction Details

Protein: hgrs-1
Organism: Caenorhabditis elegans
Length: 729 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hgrs-1.

Description E-value Query
Range
Subject
Range
gi|50745477 - gi|50745477|ref|XP_426233.1| PREDICTED: similar to HGF-regulated tyrosine kinase substrate [Gallus g...
402.0 [0..2] [702..5]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKFQRVLD QATDSTLVEP NWEGIILCTD MIRSGEVPAK PSLQAIRKRM QHENPHVVNH  60
   61 TLLVLDACVK NCGHKVHAEV ATREFMEDFK NLVTENKYDE VKNKSLEMLQ CWATAFANKP 120
  121 EYKMVVDTHN LMKLAGFDFP SLKEADAMFM AQVAPEWADG PECYRCRSVF SVFTRKHHCR 180
  181 ACGQIFCDKC SSRELALPQF GIEKEVRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.30103
Match: 1dvpA
Description: Hrs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.24093737575291 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [209-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CETCYEKKVA EVKERYPAVK KQLDAAHGRK GDSEADKAAK EKLLREKEEE DLALAIAISQ  60
   61 SEAEAKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1y02A
Description: Crystal Structure of a FYVE-type domain from caspase regulator CARP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.166244039424217 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEKQNNLYSM YNGIKPEVDG YKGAAEPVTA PPPDDSSSDP LARYLNRDYW QQKKEGKVED  60
   61 WSSRSSALSA TAPPPSEPSI APSICSTLMG PDDNSLNADI AAMSLGGTNG LNGTVSDDAK 120
  121 LQADDTMKWC QSIREQVSVM DNRIRSNLAR GRPVFNDSAI QDLFTKLTEL HSHVLSRMHT 180
  181 LDEQRGYYES LQDHLANIGE ARQAIDEMRE EHERKRQERM AEEQRLRQAQ MQQTLEMMRM 240
  241 KKHAMLMEQR EQALQRFQQQ QQEMAMRRHQ QQAYYNPQQM GYGAPPPS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [564-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPQQPPQQSY YGYQQGPQSQ APPPSSQYQQ SHASTQQQQQ QYYQHYQANQ TVTQPVQQAQ  60
   61 QQYQQQYQGY YQQQQPYQQQ AGYQNPQQHQ NYQNGTTNEN GQYQQQQSSE VKQEHQNHGY 120
  121 QQQQAQHPPA SVASNGHNGY GNVDQNAHHH QQQQPQIAEQ PLISFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

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