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Protein Overview: frm-8

General Information:
Name(s) found: frm-8 / CE32455 [WormBase]
Description(s) found:
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  • WBGene00001494 locus:frm-8 status:Partially_confirmed UniProt:Q8ITW4 protein_id:CCD72290.1 [WormBase]
  • gi|71987595|ref|NP_497672.2| FERM domain (protein4.1-ezrin-radixin-moesin) family member (frm-8) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_871647.1| FERM domain (protein 4.1-ezrin-radixin-moesin) (frm-8) [Caenorhabditis elegans] [NCBI NR]
  • gi|24636050|gb|AAN63403.1| Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 8, isoform c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32455 WBGene00001494 locus:frm-8 status:Partially_confirmed TR:Q8ITW4 protein_id:AAN63403.1 [wormpep150.fasta]
  • 32455 WBGene00001494 locus:frm-8 status:Partially_confirmed TR:Q8ITW4 protein_id:AAN63403.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • FERM domain (protein 4.1-ezrin-radixin-moesin) (frm-8) [Caenorhabditis elegans]gi|24636050|gb|AAN63403.1| Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 8, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:frm-8 status:Partially_confirmed TR:Q8ITW4 protein_id:AAN63403.1 [wormpep115.fasta.reversed]
  • CE32455 WBGene00001494 locus:frm-8 status:Partially_confirmed UniProt:Q8ITW4_CAEEL protein_id:AAN63403.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32455 WBGene00001494 locus:frm-8 status:Partially_confirmed UniProt:Q8ITW4_CAEEL protein_id:AAN63403.1| [wormORF-contam.fasta]
  • Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 8, isoform c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • FERM domain (protein4.1-ezrin-radixin-moesin) family member (frm-8) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE32455 WBGene00001494 locus:frm-8 status:Partially_confirmed UniProt:Q8ITW4 protein_id:AAN63403.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32455 WBGene00001494 locus:frm-8 status:Partially_confirmed UniProt:Q8ITW4 protein_id:CCD72290.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q8MXF0, FERM domain (Protein4.1-ezrin-radixin-moesin) family OS=Caenorhabditis elegans GN=frm-8 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 784 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSKSLQFH AGGSQSPPKR ICCSGSVDEI KDLIHTTRSS HWEPPWASWR CRLGLPYGWE  60
   61 QAKDNDGNTY YIDHLNRTTT YTDPRKTRPP DGKRTVSIRR GKDIGFGFVA AGQLPTIIQF 120
  121 VSPEGPSDGL LYANDQILEV NGLDMQNETK DNVVNAVRAA KEELQITVQQ LPQRPKSSRK 180
  181 NCKVRFTDRV LVSSTNDNNS EFPPLLPNVL RVYLENGQTR SFKYDQSTTV KQILESILEK 240
  241 LQISAKSHFS LAVEYSLGAR TSRISLLRPD CKIKSIVDLP NSEHLRCVFR LSFAPSDAFV 300
  301 LLLSDPKALE YYYQQCVNDV VRGRFAMEMR YEACIRLAAL HVQQVAYDCN ILKENNKVSV 360
  361 HRVEKEYGLG TFLPAIVLEN VKRRDVRKHI RFYLKRDSSR LVDCFGKPTI GNGYPPELEA 420
  421 CAAQFANEPS MMVRLRYIHI VSHLPSFGGR SFCVTFKESQ IDMLMQVEPR TGLLVRHPGK 480
  481 SGQPSISIGF DLIGKLVVCK ETEVASMISI RLASNPHQGL EFLVDKDDLD DLVMYIVGYH 540
  541 KVTYEKDLLL EIDDSPPKLR ELPDKAPPYS AIHTVVKSDW NYSETSSQTE KPFDPTDGPP 600
  601 SYEIANSFVQ IAFENEQNED HFDTEISRQN GESFTPKRAH FEPKKLLRAT DSLLIKNSRD 660
  661 LHAKELEIQN GGSQNDESSD TEDSSFSSPL RSPNIDRLCD GINLLVTGPP ARRASIETLL 720
  721 QNNQNPNTNL ESLILQFPTI PDENEVENDD VALPEGMQTS TTTVVANGKT RCYRNGSCAK 780
  781 SYQG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 12.39794 NMR structure of WW domains (WW3-4) from Suppressor of Deltex
    2 View Details [87..194] PSI-BLAST 9.69897 Solution structure of N-terminal PDZ domain from mouse TJP2
    3 View Details [195..784] PSI-BLAST 55.0 No description for 2i1jA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.566291652083235 bayes_pls_golite062009
  • protein binding
    		•  0.52823753548825 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle