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Protein Overview: prdx-2

General Information:
Name(s) found: prdx-2 / CE32361 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00006434 locus:prdx-2 status:Confirmed UniProt:Q8IG31 protein_id:CCD68767.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 195 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: antioxidant activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKAFIGKPA PQFKTQAVVD GEFVDVSLSD YKGKYVVLFF YPLDFTFVCP TEIIAFSDRA  60
   61 EEFKAINTVV LAASTDSVFS HLAWINQPRK HGGLGEMNIP VLADTNHQIS RDYGVLKEDE 120
  121 GIAFRGLFII DPSQNLRQIT INDLPVGRSV DETLRLVQAF QFVEKHGEVC PAGWTPGSDT 180
  181 IKPGVKESQE YFKKH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 62.522879 Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alkyl hydroperoxide reductase activity
    		•  4.29610283853788 bayes_pls_golite062009
  • antioxidant activity
    		•  3.8464796631544 bayes_pls_golite062009
  • peroxidase activity
    		•  3.43831566988273 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  3.43831566988273 bayes_pls_golite062009
  • selenium binding
    		•  2.92496040718744 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.56524997297011 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.30799114442278 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.23310780102446 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  1.47769936616412 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.32811008894503 bayes_pls_golite062009
  • transferase activity
    		•  1.26687471229876 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • protein binding
    		•  1.18479617596618 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11518182894524 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11518182894524 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • peptide binding
    		•  0.374493676068876 bayes_pls_golite062009
    		• 0.359224524631956 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  0.23291471505999 bayes_pls_golite062009
  • copper ion binding
    		•  0.178842772364502 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  0.16328723676608 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  0.0434052164026002 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle