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Protein Overview: cat-2

General Information:
Name(s) found: cat-2 / CE32103 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00000296 locus:cat-2 aromatic amino acid hydroxlase status:Partially_confirmed UniProt:P90986 protein_id:AAV58889.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: axon [IDALink to PubMed article]
    Biological Process: response to food [IMPLink to PubMed articleLink to PubMed article]
    mechanosensory behavior [IMPLink to PubMed article]
    dopamine biosynthetic process [IMPLink to PubMed article]
    serotonin biosynthetic process [IEALink to PubMed article]
    dopamine metabolic process [ISSLink to PubMed article]
    habituation [IMPLink to PubMed article]
    aromatic amino acid family metabolic process [IEALink to PubMed article]
    L-phenylalanine catabolic process [IEALink to PubMed article]
    regulation of locomotion [IMPLink to PubMed article]
    catecholamine biosynthetic process [IEALink to PubMed article]
    Molecular Function: iron ion binding [IEALink to PubMed article]
    phenylalanine 4-monooxygenase activity [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    tyrosine 3-monooxygenase activity [IEALink to PubMed article][ISSLink to PubMed article]
    tryptophan 5-monooxygenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLRYMRRRG SGEDHEEEPR GVTVIATKVA ENSKNPRRYS LVHQASCETQ HHKGIRRQNT  60
   61 IQHRKQLTDQ MRCQKILQQL NDEGIEVIFT ANDVTPIEFS IILTSTDPTL SNFVSDILQN 120
  121 MSSAKVQICH VETRGNEASH DVLLACKATK NQLIHSAELL TQNHVALTKF SIFAKKLSDE 180
  181 KNQSQIWFPR HISELDQCSK CITKYEPTTD PRHPGHGDVA YIARRKFLND QALEFKFGDE 240
  241 IGYVDYTEEE HATWKAVYEK LGDLHLSHTC AVYRQNLKIL QEEKVLTADR IPQIRDVNKF 300
  301 LQKKTGFELR PCSGLLSARD FLASLAFRVF QTTTYLRHHK SPHHSPEPDL IHELLGHVPM 360
  361 FSDPLLAQMS QDIGLMSLGA SDEHIEKLST VYW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 40.045757 No description for 2qmxA was found.
    2 View Details [83..393] PSI-BLAST 112.0 Phenylalanine hydroxylase N-terminal domain; Phenylalanine hydroxylase, PAH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.402888380251327 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle