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Protein Overview: CE31670

General Information:
Name(s) found: CE31670 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00013866 locus:cbs-1 status:Partially_confirmed UniProt:G5EFH8 protein_id:CAA88980.3 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 704 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tryptophan biosynthetic process [IEALink to PubMed article]
    threonine biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    cysteine biosynthetic process via cystathionine [IEALink to PubMed article]
    cysteine biosynthetic process from serine [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    tryptophan synthase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    cystathionine beta-synthase activity [IEALink to PubMed article]
    threonine synthase activity [IEALink to PubMed article]
    cysteine synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQNEVSATH GSTKKGITYN TILEAAQRPT PLVPLKKLKV EHQLQSDIYV KLEYLNIAGS  60
   61 LEDRTADKAF QFAEEIGVVR GDEVFVTAGG SAAISYATVA AVKGIKLTIY APKGEFDLVD 120
  121 TVLHTLGVKT VELPFGTFAE ARVQTDEAAQ QKGVFSLNKF TTNAAFVANL QKTALEIEKA 180
  181 VNNKSIGKVG AVVIPLNTGA AAAGIAAYYK GIGEHGVRVV GVTCKKDTIP EMGLDLKNDL 240
  241 LQEYNVEKRE VEEDEAYSFT RHLIGTEGIM AGPSSGAAVL EAIKLAKELP AGSTIVVVLM 300
  301 DGIRNYLRHF LDDDWITANK KDVVTRKDGP QPNSIYDPKV LVYDPTKLAG EWTQDPETKS 360
  361 WSHSEVEFNK FNPERPLVLD TVLDAIGKTP LVKLQHIPKA HGVKCNVYVK CEYMNAGGST 420
  421 KDRIAKRMVE IAEKTGKPGK LVPGVTLIEP TSGNTGIGLS LASAVRGYKC IITMPKKMSK 480
  481 EKSIAMASLG STIIRTPNEA GFDSPHSHIG VALRLKSEIQ DAVVLDQYCN PGNPLAHYEE 540
  541 TAEEIIYDMG DKHIDLVVLT AGTGGTVTGI SRKIHERIPT AKVVGVDPHG SILAGPAETD 600
  601 IDFYEVEGIG YDFLPGTLDT SAIDYWAKSH DKESFLMARE LIRSEGILCG GSSGCAVHYA 660
  661 LEECKSLNLP AEANVVVLLP DGIRNYITKF LDDDWMNERH FLDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..322] PSI-BLAST 67.522879 Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a hyperthermophile, Pyrococcus furiosus
    2 View Details [323..704] PSI-BLAST 107.0 Cystathionine beta-synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
    2
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle