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Protein Overview: unc-25

General Information:
Name(s) found: unc-25 / CE32012 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00006762 locus:unc-25 status:Confirmed UniProt:Q8I4D9 protein_id:CAD45606.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: inhibitory synapse [IDALink to PubMed article]
    synaptic vesicle [IDALink to PubMed article]
    neuronal cell body [IDALink to PubMed article]
    axon [IDALink to PubMed article]
    Biological Process: carboxylic acid metabolic process [IEALink to PubMed article]
    synaptic transmission, GABAergic [IGILink to PubMed article]
    gamma-aminobutyric acid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article][ISSLink to PubMed article]
    glutamate decarboxylase activity [ISSLink to PubMed article]
    carboxy-lyase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCSRILLRK SCEDVLRLGV RTGHPRFFNQ ISCGLDLVSM AGEWLTATAN TNMFTYEIAP  60
   61 VFILMEKSVM ARMWEAVGWD PEKADGIFAP GGAIANLYAM NAARHQLWPR SKHLGMKDIP 120
  121 TLCCFTSEDS HYSIKSASAV LGIGADYCFN IPTDKNGKMI PEALEAKIIE CKKEGLTPFF 180
  181 ACCTAGSTVY GAFDPLERVA NICERHKLWF HVDAAWGGGM LLSPEHRYKL AGIERANSVT 240
  241 WNPHKLMGAL LQCSACLFRQ DGLLFQCNQM SADYLFQQDK PYDVSFDTGD KAIQCGRHND 300
  301 VFKLWLMWKS KGMEGYRQQI NKLMDLANYF TRRIKETEGF ELIIENPEFL NICFWYVPSK 360
  361 IRNLEPAEMR ARLEKIAPKI KAGMMQRGTT MVGYQPDKQR PNFFRMIISN QAITREDLDF 420
  421 LIKEIVDIGE SLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..433] PSI-BLAST 95.69897 No description for 2okjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle