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Protein Overview: nhx-8

General Information:
Name(s) found: nhx-8 / CE31092 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00003735 locus:nhx-8 Sodium\/hydrogen exchanger status:Confirmed UniProt:G5EBN7 protein_id:CAA22320.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 681 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILANGVTW QLWESTLNQG TATSGIMRFA LKTALSICIF LLIFQTVDSD SSDSSASASV  60
   61 VSGAVKSEDT VVAVNKTDVL GEAIDANATS LEQHGAAIVG NVSEEKKRSL AIFFILFVIM 120
  121 LATLVVHMLI VSKIHWMPES LAIVALGALI GSILSYSRRD WSEIEALSPD VFFLVLLPPI 180
  181 IFENAYNLNK GYFFSNFVPI LTFAIFGTTI SAMVIGAGLY ILGAIGLIFE FTFFECFAFA 240
  241 AMISAVDPVG TLAIFQAVKV ESLLYMLVFG ESMLNDAVSI VLAATALRHA KPSFNSLPAS 300
  301 EIITSAFVTF TEMFFFSACL GVGIGLLSAL LFKHVDLRKT PSLEFALLLI FSYIPYGFAE 360
  361 ALDLSGIMAI LFCGISMSQF TRHNVSPIAQ ITFRHTFRTI SFVAETSTFA YIGMAFFTIK 420
  421 LNFAPWLIFW SVVLCLLGRA CNVFPLAYLV NQCRKDVQIS MKNQIIMWFS GMRGAVCFAL 480
  481 VLYMDLDKEK KSILLTTVLF LILFTTIFLG GSALPFISFI NRCYPNERQR KRRRTPRNKE 540
  541 STGNSSALMM SKTQEMSFFG SDDWGPKKSA LDATSSAGRI MRQLFVRKFT AIERLENRDK 600
  601 LAALTKRALA SDQMTDSDDV EFGGGGGVGG GGRMKDDVTP TRGRSGSRNS SDVIISAGGG 660
  661 GVSGEHHLLI SSGSDSSTNE F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] MSA 2.167992 View MSA. No confident structure predictions are available.
    2 View Details [101..227] MSA 6.003996 View MSA. No confident structure predictions are available.
    3 View Details [228..379] MSA 2.006991 View MSA. No confident structure predictions are available.
    4 View Details [380..525] MSA 4.011995 View MSA. No confident structure predictions are available.
    5 View Details [526..681] MSA 3.657997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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