YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: apx-1

General Information:
Name(s) found: apx-1 / CE30819 [WormBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • WBGene00000168 locus:apx-1 Anterior pharynx in excess protein 1 status:Confirmed UniProt:P41990 protein_id:CCD72794.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 515 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: cell communication [IEALink to PubMed article]
    embryonic pattern specification [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    lateral inhibition [IGILink to PubMed article]
    morphogenesis of embryonic epithelium [IMPLink to PubMed article]
    regulation of vulval development [IGILink to PubMed article]
    Molecular Function: calcium ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNFSSLLTT IFLCIISSAT GSGTIELLIS SPQTVLVEPT VCANFECAAP DDLSLARKVQ  60
   61 RRVPLRFGTG QYHGEARERI DLHLKIIEPT SNEILALQHH RPAADTEWNS DAPIVIETSR 120
  121 GFNVTVQLRN LCSSNYHGKR CNRYCIANAK LHWECSTHGV RRCSAGWSGE DCSNPICAGG 180
  181 CSNRGRCVAP NQCSCADGFN GTRCEQCLPR AGCVNGDCVN ETPNTCKCRD GFIGDRCDID 240
  241 IKICSLEKPC ANGGICSIDS SSSTGYKCHC PFEFVGSQCK TPLSKVRCSA EHVCKNGGAC 300
  301 ISMDDTNIQC KCRRGFSGKF CEIGNHGDCS AMRCSAGETC QISGDFAICV ENDELLLTTN 360
  361 KPAETTKSVE KWREPRKTAN DEQASDELQL RLIAAICVLF SVCVIGLALV SFFFYMHSFS 420
  421 KWKHPSSQQA GGSTILPTTT SIPMSTTSSG TGSPVYKVCI IDSEHRGNAP GSSSDSEPDH 480
  481 HCPPPHRHSP PPAYSSLVLY KKVPMAADDE SSFRV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..419] PSI-BLAST 8.69897 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    2 View Details [420..515] PSI-BLAST 5.522879 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ErbB-2 class receptor binding
    		•  2.49988032150831 bayes_pls_golite062009
  • receptor binding
    		•  2.31571280660349 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  2.14752073450101 bayes_pls_golite062009
  • binding
    		•  2.14092582858845 bayes_pls_golite062009
  • protein binding
    		•  1.87564165872234 bayes_pls_golite062009
  • signal transducer activity
    		•  1.48171797015526 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.48171797015526 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  1.08974638257724 bayes_pls_golite062009
  • growth factor activity
    		•  0.402016723620225 bayes_pls_golite062009
  • pattern binding
    		•  0.0196006376432096 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle