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Protein Overview: shc-1

General Information:
Name(s) found: shc-1 / CE30804 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00018788 locus:shc-1 status:Confirmed UniProt:Q9TYT3 protein_id:CCD68061.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 316 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    Biological Process: response to metal ion [IMP]
    positive regulation of kinase activity [IDA]
    response to endoplasmic reticulum stress [IMP]
    Molecular Function: protein binding [IEALink to PubMed article]
    mitogen-activated protein kinase kinase binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNVEPSFAE ELRSSGVSLS ATYLGSVPVV ESINVMVSEM RVQVVSECIQ HVAATVGVTA  60
   61 AREINPVVSR VIGEVKKENF PVDINISSKM IKIIKQSRLI QRHPFSFFSF GAQGQKGTDT 120
  121 ELMFGYIAKN KDGTDRRCHV VFIEDVHKLI DVLTTAINVN TFDAQANAST SNDGFTVPAP 180
  181 PMRHRSSLHR QSFVSNCRAP TVTEDVVGKV WYHGNLSRED AQALLKTEGD FLVRQSDHTP 240
  241 GKYVLSGRTA ENEHKHLILL DNHNRVRTRD RTFSNISELI DYHVNNGMAV RSEGRDRETS 300
  301 LNLIRPVPCP GSDDIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] PSI-BLAST 38.522879 Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
    2 View Details [88..316] PSI-BLAST 41.39794 No description for 2h8hA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle