Protein Overview: itr-1

General Information:
Name(s) found:	itr-1 / CE31690 [WormBase]
Description(s) found: Found 16 descriptions. SHOW ALL	WBGene00002173 locus:itr-1 Inositol 1,4,5-trisphosphate receptor itr-1 status:Partially_confirmed UniProt:Q9Y0A1 protein_id:CCD63767.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1713 amino acids
Gene Ontology:
Cellular Component:	membrane [IDA][IEA] endoplasmic reticulum [TAS] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of pharyngeal pumping [IGI][IMP] ion transport [IEA] muscle contraction [IMP] calcium ion transport [IEA] cell adhesion [IEA] blood coagulation [IEA] defecation [IMP] reproduction [IMP ] rhythmic behavior [IMP] elevation of cytosolic calcium ion concentration [IDA]
Molecular Function:	inositol-1,4,5-trisphosphate receptor activity [ISS] ion channel activity [IEA] calcium channel activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYDYRRRVL ERNIGMALPS RKLTIANSID HGNNGNLHIG DIISLYTESS SNQEQRGFLS  60
   61 TLGLVDDRCI VELKDGRPES PPKKFRDCLF KVCPVNRYAA QKHLWTEQKR FQTGDSMFDD 120
  121 DLMNKLKVAA DKEREENESE FQKTLGNVIQ YGSMVQLLHV KSNKYITVQK NSPAKRERNA 180
  181 MKVYLDRAGN EGSWFIIEPA YKHYAIGDNV SAGNKISLIP NSVSTTQAGH VKSQLHLSSF 240
  241 NLLDHQSAAE VNCLNEPTEW QVFMFLLFDE NQQNSVKSGD VVRLFHADQQ TFLTLDTIPK 300
  301 QNPPTDVVFL RMTNRPSAAD ATSSRALWEV QVVQTNAYRG GTAKWNKAYR FKHLATDMYL 360
  361 SAEPSQVQVK PAMNGRRASL IYSKTNNPMA MYSDGPNGVT NESTDTTQQN IPSVWVLGPT 420
  421 KSEFPEEDAN LLFQLDPSTF MKSNKEVPRR SYVRLLHQSS DKWVHATNAT EKQNLHYSSK 480
  481 NEKGWVKVIC EKNRVDKETF ALLPVNPDEV RDLDFANDAC KALRNFIKLI KIGQVISKES 540
  541 INSTTQLLID CILFVTNSSD HLADPLKISD FSPSRDRQKL LREQEVLNQV FLLLKAPFLP 600
  601 RQGTTELGPL LSSPSELSDS RNEIFKTMFQ LCYCLLKYSQ VSYRKNQEFL AEKFGEIQEQ 660
  661 IGFDLMAEDT MTAVLHNNPK LLEKYVKTPH VERFVELVRN NRQGKFLDYL ADLCVCRGEA 720
  721 NKKIQELICT SVLSSKHRDI FMDTKIIDGE IEVGWAPNFR KLVDIAEGAK SNSDDAEHLD 780
  781 YYRHQLDLLS QMCQEQQYLA IDPPPERRLM NISQQLPAEL VLQCMSDNRL PYDLRGSFTR 840
  841 LMLHLHVVRG SPMSAIRHAR LWWSIPENVN VSTYESVSVE AYSDGSRMRI GEGIAHKVLA 900
  901 TVETYLMGLR NQSMEERQSV NSSKLTYEIV NLAKALAQFN FYSFNDLLQL TQNLLAIINE 960
  961 GPATEQVPSH RAMVNAIRNM SKSMMRGGNK ENSKDLAKTP SVTAEEAGRT KEGRALNVKT1020
 1021 KLIVAEILQF VMDVRRDYRI TMALSWFKNV FPCDEDGSLM HSASINERMA SELYDAIYRS1080
 1081 SGHELHLDGR DGQLLLAILL QMTMSDYPPL TSIALKVFFR HFTQYQELLE DLKQVQLLVS1140
 1141 NNDVENYRQI DRDLFILKNL TEKSELWVHG DRHHSIDTKE VDEKERTTEH DLLDHDLKSP1200
 1201 RAFDSGDSME ALMAVLNEHY PSIRNECLQL LNRLLIKDDR NDAAVALQEL SDKAPLIAYP1260
 1261 LIRQMLVRLT GMCYRKGDPK PDTMNQQLLK NMRVYEVVLE FISVPHDKKH DHDMMKLITL1320
 1321 SHEFLRSFCK TNKENQSRLY KFISYEKDAK EGMLRVETIE EVGTLVAIFR NNRELASNVP1380
 1381 EELIAHIVGL IEHNSRNPIF LELLQALVCV YDKEIESGQE KVANEICAAS DEVRQLYVDN1440
 1441 ASFEELEAMM KDEKESKGRS SDSRRKLKYH IELVRLLAMC TRGKNGNTEL KCASQIPMDH1500
 1501 IVRVVTAKQC LVEVKTVYLQ LLLHCYIDTD AEMKDAYKTE YVDHILNNLL EDIRSLRVEK1560
 1561 LTGAETATLE HYICHTVTEV LIKFFEAPYS ALQQAKVDVH HHKKTFSEVL LELTYLEKGK1620
 1621 LRGSKSSRNW YRVAECIKRL TKWAEEHNIT LPATLAGPQM SGQTSVRQKW QQAASSAKWI1680
 1681 GIGKPVITLV VETQSSKYAQ SWSSTLWNIK LYD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: itr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: