Protein Overview: plc-1

General Information:
Name(s) found:	plc-1 / CE31495 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00004036 locus:plc-1 status:Confirmed UniProt:G5EFI5 protein_id:CAD44124.1 [WormBase] gi\|71989048\|ref\|NP_001024619.1\| PhosphoLipase C family member (plc-1) [Caenorhabditis elegans] [NCBI NR] gi\|22265911\|emb\|CAD44153.1\| C. elegans protein F31B12.1c, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|22265832\|emb\|CAD44124.1\| C. elegans protein F31B12.1c, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep88.fasta] Hypothetical protein F31B12.1c [Caenorhabditis elegans]gi\|22265832\|emb\|CAD44124.1\| Hypothetical protein F31B12.1c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed TR:Q8MM09 protein_id:CAD44153.1 [wormpep150.fasta] 31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Partially_confirmed TR:Q8MM09 protein_id:CAD44153.1 [wormpep130-phg-ecoli-orf-rand.fasta] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Partially_confirmed TR:Q8MM09 protein_id:CAD44153.1 [wormpep132.fasta] 31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed TR:Q8MM09 protein_id:CAD44153.1 [wormpep150-phg-orf-ecoli-rand.fasta] locus:plc-1 phosphoinositide-specific phospholipase C status:Partially_confirmed TR:Q8MM09 protein_id:CAD44153.1 [wormpep115.fasta.reversed] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed UniProt:Q8MM09_CAEEL protein_id:CAD44153.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed UniProt:Q8MM09_CAEEL protein_id:CAD44153.1\| [wormORF-contam.fasta] PhosphoLipase C family member (plc-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein F31B12.1c [Caenorhabditis elegans] [nr-271106-contam.fasta] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed UniProt:Q8MM09 protein_id:CAD44153.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31495 WBGene00004036 locus:plc-1 phosphoinositide-specific phospholipase C status:Confirmed UniProt:G5EFI5 protein_id:CAD44124.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE31495 WBGene00004036 locus:plc-1 status:Confirmed UniProt:G5EFI5 protein_id:CAD44124.1 [wormpep246-ecoli-contam.fasta] CE31495 WBGene00004036 locus:plc-1 status:Confirmed UniProt:G5EFI5 protein_id:CAD44124.1 Phosphoinositide phospholipase C [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta] Isoform of G5EFI8, Phosphoinositide phospholipase C OS=Caenorhabditis elegans GN=plc-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1895 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	signal transduction [IEA] small GTPase mediated signal transduction [IEA] lipid metabolic process [IEA] gamete generation [IMP] reproduction [IMP ]
Molecular Function:	phosphoinositide phospholipase C activity [IEA] phospholipase C activity [IEA] guanyl-nucleotide exchange factor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNWDTLKGVL KTRRLTKRTI PAYIHPTSRS DSTSSTQSAT AGFILNEEPI TLFRLELERL  60
   61 QYILHFPEEV AFQLSSTEYQ LFYSIQPMDY VRYVSCDLTS VPVSENPSPV RNLVKRLSEV 120
  121 SSWITHVIVS QPTHDDRKVA LTAILRIVET CWNIGNFNAA VEVLMGLKSE KLRPFWLSLR 180
  181 QEEKSQFDSL CETLLPANQA LPSQAYINAV QRALRMPQSR VIPFFGIFLR DLYAIVNDLP 240
  241 NIVVIGQEGE TQKLEFMSDP NGEDHFSSRI GVGGLLNADK INLVAIVLDN LELFHRHSRT 300
  301 MIKLLEEQAV PPIQIPQNER EQKEKEAKTY EPVQVVRGSS HGVALIPLDT LTFDLDVIQR 360
  361 LQHGTTVIHY EPDSGRSNLC LLRLDPSCGQ INWHKISYSV NKDPKEKDVL AKVSVSNLQP 420
  421 LDSGRGAPSP MPSGRTPGTG GVGVEEGELK LSVVKGVELV DSYDIDIEAI YRRHSMEEMS 480
  481 VPVSCWKVSH GQLLSDNEFI YFLAPQQIAQ FWTNGLQSVV KSLQGQQRYP DRRMLWIKNV 540
  541 YLSLYEITGE SNCGPRPFEA LQAFGLSQTN TNATRPNDSS LSSEPGGAKS RLKNLKNAMQ 600
  601 KKLRGASREG SRSQSPQPHS PLVRPPSIKS QISSQSGPPG PNSPGYLLKP RGEPANSDAG 660
  661 DIDSIYTPRS RTPTSSSYGG RSVGGRSCKS WRSRGGETPN SGSISSSGQM SIQVSGLSGP 720
  721 SGKEFQEKPL TLVEFAELFR LFNTRMRKDL RDVFNDVLST ATTPQHCPKR ERDRHSPRMQ 780
  781 SRLASVSNSY NADFLSNDFL TRNTAVTSHH ISEKQNKIYN ALALASVNSM GGLMDTSRSS 840
  841 MLTPQMLRAF VNTHQMEQID EQTAIKLIQD HEPDGICRQK NQMSFEGFTR FLCDPVNFAF 900
  901 VPETIEPDEE DLRYPLSHYY INSSHNTYLT GHQLKGPSSS EMYRQVLLTG CRCVELDCWD 960
  961 GDDGLPLIYH GHTLVSKIGF RQVVEIIKKS AFITSDLPVI LSIENHCSLQ QQAKMAQMFK1020
 1021 TVLGDLLVSN FLFEADFSDS PRLPCPLQMK NKILIKNKKM IVDPPTPLPM IERGAVQRGE1080
 1081 TQLNLHRKQS KNSYESSTVD EVEDDDLDEF LDDEENEEDD QEEVQVRSEK EDSPKTSKRA1140
 1141 EKSARNIKQQ DSLCSDHSVE QAKPSTSKTT SKTNDRKTED EVLYAQLAQN AIRNQQPRKN1200
 1201 NTGVQIAPEL SDIVIYMQAT KFKGFPPVDG IQSPRIMEEG PASASLSFSS RARTPSNLLN1260
 1261 TPAPPRRQRS STQLSQELAA EFLGSVRANA TATCYQVTSL NENAAKKLMK RHPAKCVSYT1320
 1321 RDHLIRTYPS AKHYDSSNFN PINCWAHGMQ MVALNFQTPD VIMAVNQAMF EQSGNCGYQL1380
 1381 KPRCLWDESH LLYNKFLPLS KDIAGHSALL LNLTIISGQH VYPNTHYASL YVEIEVIGIH1440
 1441 NDCVREKSKV VQRNSVNPIW NHTTQLRIAC VDLAFLRIAV CDSGQNGRVV AHRVVPVKCI1500
 1501 RPGFRHLPLR TPTNLPIDNA MIFLRTRFEQ EEHIYLHDDD SNTYCNLEHT LAYRTDLTPN1560
 1561 LSPTPILKKQ IFVLRITGAF ADETAITVHS ESGSTVKTVM QQALLNAGKN ADQVEEYVLI1620
 1621 EESLPAPSGE DPIEQRVLPL NEPIMDAVAC WNGSMRRFVL RKKGSDPSSR AWITSIIKSG1680
 1681 TSGSSTSVSP SPLTKDGHVK SASSNQLHGR SLDTDAFGEH LEVTEGKWLN PRARSMGDTF1740
 1741 LVCVHNVSED QPYAILRAGI HSTAADIIRQ VFVKARRSNV DDSEFVLVEE TCDDPKLNQG1800
 1801 QMTPKYPNNR TTSRVLGQNE NVWKAQSRWK SMGRFVLENR KDTVHATLEK GRRVESTTSS1860
 1861 STTTRKISLS SVRSIGLPRK FSKFGKSLTM DAGPK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: plc-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: