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Protein Overview: tbc-1

General Information:
Name(s) found: tbc-1 / CE31485 [WormBase]
Description(s) found:
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  • WBGene00008974 locus:tbc-1 status:Confirmed UniProt:Q93534 protein_id:CAB01744.2 [WormBase]
  • gi|25152654|ref|NP_510485.2| TBC (Tre-2/Bub2/Cdc16) domain family member (tbc-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|22265808|emb|CAB01744.2| C. elegans protein F20D1.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE31485 WBGene00008974 status:Confirmed TR:Q93534 protein_id:CAB01744.2 [wormpep150.fasta]
  • 31485 WBGene00008974 status:Confirmed TR:Q93534 protein_id:CAB01744.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • RabGAP/TBC domain containing protein (73.2 kD) (XP593) [Caenorhabditis elegans]gi|22265808|emb|CAB01744.2| Hypothetical protein F20D1.2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Confirmed TR:Q93534 protein_id:CAB01744.2 [wormpep115.fasta.reversed]
  • CE31485 WBGene00008974 locus:tbc-1 status:Confirmed UniProt:Q93534_CAEEL protein_id:CAB01744.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31485 WBGene00008974 status:Confirmed UniProt:Q93534_CAEEL protein_id:CAB01744.2| [wormORF-contam.fasta]
  • Hypothetical protein F20D1.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • F20D1.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE31485 WBGene00008974 locus:tbc-1 status:Confirmed UniProt:Q93534 protein_id:CAB01744.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • TBC (Tre-2/Bub2/Cdc16) domain family OS=Caenorhabditis elegans GN=tbc-1 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of Rab GTPase activity [IEALink to PubMed article]
    Molecular Function: Rab GTPase activator activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGETGPTNNT SFSSLDDNWE TDVNVLSSEL GDLDTEGNDK SDWMRLLGVS MKPNPLDDWD  60
   61 QLYNLNNQCA LRNDCRKLAN GLKNKRSVPE LESFLTLYCK KRGMDYIKDI GWLTILEKIL 120
  121 LLNVPAAHEF NVFFAFTTKY IPKDTRPDAQ IFDLFRLLLQ YHDPQISNHL ESLHCSPSMY 180
  181 TKNWFATLFS SSMSTESCHE LWKLYIEQGD PFLVFHLAIV FLINAKDEIL QVKRDEKEKA 240
  241 VQILENMAAQ LSVEDVPDFF QLALHYSDKT PECIRKDFHY IIFGANFDEE VKEIQMNKML 300
  301 CLPIPAIDLT SHDEISSGSV NFFIVDTRSN TDFDSGHFVS SFNLDCVAIV DEPEKFEIAL 360
  361 NSLECYKTSR RDEDHYLILG YGSDEEDNYM NMLIAMFIQK GKLHVSFVQG GYKKLHDCIG 420
  421 QHNRWELIAM HSEDRCELCS SEKASPKWGF FSKMKSAVSN TSSRMKERVE AVVFPIGEEK 480
  481 KLDDKHADSK QRHGKRYRQQ SVFTIDENSD DEMAAGAAVD ENPKEEILLS KEFTETFECQ 540
  541 EVFRDGSING HIALTRTHIY VLHDVPGKQG YVTTEARHAL STVVAVTSRR SVPEMLTFKL 600
  601 GYEMNGSSKI TAVHKLYVPK AGECAKAVKL AIYALRPLPD A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..289] PSI-BLAST 43.69897 No description for 2qfzA was found.
    2 View Details [290..441] FFAS03 2.67 Erk2 binding domain of Mapk phosphatase mkp-3
    3 View Details [442..528] deduced N/A No confident structure predictions are available.
    4 View Details [529..641] MSA 2.036954 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.708103811735445 bayes_pls_golite062009
  • protein binding
    		•  0.279521784602446 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle