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Protein Overview: ipp-5

General Information:
Name(s) found: ipp-5 / CE30857 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00002146 locus:ipp-5 Probable type I inositol 1,4,5-trisphosphate 5-phosphatase status:Confirmed UniProt:Q17848 protein_id:CCD63797.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 409 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: inositol phosphate-mediated signaling [IGILink to PubMed article]
    epidermal growth factor receptor signaling pathway [IGILink to PubMed article]
    ovulation [IMPLink to PubMed article]
    phosphoinositide dephosphorylation [ISSLink to PubMed article]
    Molecular Function: inositol or phosphatidylinositol phosphatase activity [IEALink to PubMed article]
    inositol-polyphosphate 5-phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQYLLITAN VGSLFEPDAR LHTSWIKTVA DQVESVDPSF FVIHLQETGG KKFTECSQQV  60
   61 PIIINRLSTA LPKFDLLRAY VDIDYEAIEY TALGALCFIK RSLWSNVSQF NFHTKKYEQL 120
  121 TSPKEVVTHG LENYPYVVKH KFPKDFWPSI KWGRKGYMQT RWKIENKVFD FVNAHLFHDE 180
  181 SNLALIHENP QLYSQNRKRA LDFVLAELSS KENGCTPLLF VFGDLNFRLD SRSFLNRLTE 240
  241 RTAQHPVADQ EQMGSLADGL QASAANLQVI THPSENLRRT VSAIEFRRES DSDDSQNSCV 300
  301 LRIEKKKFDY FNHKKLLDDW RSYRDDDKET ENFQSMFEMH INFPPTYPWS EDPENSETLM 360
  361 KTRAPAWCDR VLMNKNAYSL VEEGEPQYRS FGMETCTGDH KPVMLTFNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..409] PSI-BLAST 50.522879 Synaptojanin, IPP5C domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, acting on ester bonds
    		•  6.18859979894085 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  5.86270793496562 bayes_pls_golite062009
  • phosphatase activity
    		•  5.39890422452758 bayes_pls_golite062009
  • hydrolase activity
    		•  4.60076024097939 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  3.5663863902952 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
    		•  3.32245303567348 bayes_pls_golite062009
  • phosphoinositide 5-phosphatase activity
    		•  3.32245303567348 bayes_pls_golite062009
  • inositol trisphosphate phosphatase activity
    		•  2.32855198081691 bayes_pls_golite062009
  • phosphatidylinositol bisphosphate phosphatase activity
    		•  2.32361963718068 bayes_pls_golite062009
  • inositol-polyphosphate 5-phosphatase activity
    		•  1.86706054276134 bayes_pls_golite062009
  • catalytic activity
    		•  1.76511376991978 bayes_pls_golite062009
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
    		•  1.47273981396735 bayes_pls_golite062009
  • binding
    		•  1.10604548818653 bayes_pls_golite062009
  • protein binding
    		•  0.476649214025345 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle