Protein Overview: dnc-1

General Information:
Name(s) found:	dnc-1 / CE30718 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00001017 locus:dnc-1 status:Partially_confirmed UniProt:Q23542 protein_id:CAA93427.2 [WormBase] gi\|25151912\|ref\|NP_502033.2\| DyNactin Complex component family member (dnc-1) [Caenorhabditis elegans] [NCBI NR] gi\|20803779\|emb\|CAA93427.2\| C. elegans protein ZK593.5, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep79.fasta] CE30718 WBGene00001017 locus:dnc-1 dynactin status:Partially_confirmed TR:Q23542 protein_id:CAA93427.2 [wormpep150.fasta] 30718 WBGene00001017 locus:dnc-1 dynactin status:Partially_confirmed TR:Q23542 protein_id:CAA93427.2 [wormpep130-phg-ecoli-orf-rand.fasta] ortholog of Glued p150, DyNactin Complex component DNC-1 (148.4 kD) (dnc-1) [Caenorhabditis elegans]gi\|20803779\|emb\|CAA93427.2\| Hypothetical protein ZK593.5 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:dnc-1 dynactin status:Partially_confirmed TR:Q23542 protein_id:CAA93427.2 [wormpep115.fasta.reversed] CE30718 locus:dnc-1 dynactin status:Partially_confirmed TR:Q23542 protein_id:CAA93427.2 [wormpep80.hongbin] CE30718 WBGene00001017 locus:dnc-1 dynactin status:Partially_confirmed UniProt:Q23542_CAEEL protein_id:CAA93427.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE30718 WBGene00001017 locus:dnc-1 dynactin status:Partially_confirmed UniProt:Q23542_CAEEL protein_id:CAA93427.2\| [wormORF-contam.fasta] ZK593.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein ZK593.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE30718 WBGene00001017 locus:dnc-1 dynactin status:Partially_confirmed UniProt:Q23542 protein_id:CAA93427.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE30718 WBGene00001017 locus:dnc-1 status:Partially_confirmed UniProt:Q23542 protein_id:CAA93427.2 [wormpep246-ecoli-contam.fasta] Isoform of E2JKZ0, DyNactin Complex component OS=Caenorhabditis elegans GN=dnc-1 PE=1 SV=2 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1326 amino acids
Gene Ontology:
Cellular Component:	centrosome [IDA] cytoplasm [IDA] dynactin complex [ISS] kinetochore [IDA] midbody [IDA]
Biological Process:	establishment of mitotic spindle orientation [IMP] pronuclear migration [IMP ] centrosomal and pronuclear rotation [IMP] morphogenesis of an epithelium [IMP] embryonic development ending in birth or egg hatching [IMP ] nuclear migration [IMP] chromosome segregation [IMP]
Molecular Function:	cytoskeletal protein binding [ISS] dynein intermediate chain binding [ISS] microtubule binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFEIGTRVK TSSGNGRVVF CGQTQFAEGD WVGVILDTAT GKNNGTVQNV QYFECEPNFG  60
   61 VFVKSSAVEL EDASKRSGLK APAASAIRKD SSVMSRSAGS KASPGSSPGM SPAASSEKLT 120
  121 GRQTGMGPRS MSKLADPNES RMVREFSNLS QSSVASSRAS ASASKPRPQF TAPDPRRQSL 180
  181 APPKKASTTT APVSKPSLSK PRQSLAPSKP AEVTPQKPVP AAQASEAGDP PNELPLPTMT 240
  241 ESGTELPKES VLSRAKKIDD TGPAAPMSPL STTAAARPRT TSVSSSAQES STEIEYLRNQ 300
  301 VKELTEKLEA ARVKRKEDHT KVMELDRVSF ELRSSEEVRS RLIQKITELE KQIGDERIAK 360
  361 EQLQAWQDEN KVLLSDHQDT MEMATIEKEL AEERADSLQN DVLTLTEKLE SMETELEILK 420
  421 EEMANGGGAA QVGNSVQMKQ IEIQNDKLKD ALIKLRDLNA QATLDRQKAV DEAERLKTEN 480
  481 SELIRVAENL KRQTEIAESK IAGFQEQIDA AMGAEAMVTQ LTDKNFNMEE RIMQLEETIE 540
  541 DMEEARDLDE QLAEVQKQQV KDLMKEIEQL KIHIHELNGR IRDEQKHAVD LSQTILKFRE 600
  601 RMANLNSQIQ DQKDQVLSLE EQLHGHISVD NDRASMVNQL QISANRNFAE DVERQVNAIE 660
  661 VEFARRQAGY LKAFLPDNFS RVGGENDSIL LVVMLPRLAA KTKLFASLAA QCFPQVPGGM 720
  721 RREHVTKSHK GEQWAHVARV NYLANSINAA LGKLESAIGE TTVEVLIKLT ETYGEMSTHE 780
  781 KTVDQYLELL KKSRFDENTS LDSFVRPLVY FQNMFSLHIG GDGFNAAHWV SEICASLSAG 840
  841 LAYCRVNTQR ISYFLQESIT AGEVYNMLQT LNDEFAACES VILKAYRLLP GNVSGSEQKI 900
  901 LKLESEFTED LLNSVVQLDK MVSILQEVCA NGALSFGGIS ETEGFDEKRV KEMINAVLGK 960
  961 QDGYIAIDKT FDPIRALIKS LRDSLEKVNS TLESAKMEHS APEKKSFPPL LDRAHHRKQA1020
 1021 AQEAEGLRWQ MEKKDNEMLE LRKQMKARIE DVSNYKLRLD MAESRLNSTD KAEGDKVKHL1080
 1081 EEKINQMVAD HRRKQIEYDE SMDALQREMK EVESDNLELK QRANKISKEA LWKNIQSMET1140
 1141 RSSGSPSVPM STSIDEGGAS RGEVVFLENQ LNKQTNARKR AELEVRKLKG ELAQAGSKRF1200
 1201 SAVPGLISGP ITLESQTRQD LLLKLIDNLH DESLRLRREE VNHQAYVPSN PKISTEKMVE1260
 1261 EMEIFNVKRE QFFDKLNSVN RRLRRVWFDA WGEEYPFEIA AKSRPIVAVP EPKKFEEISA1320
 1321 KWGIVW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: dnc-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: