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Protein Overview: ctn-1

General Information:
Name(s) found: ctn-1 / CE30316 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000832 locus:ctn-1 status:Confirmed UniProt:H2L012 protein_id:CCD70913.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: actin cytoskeleton [IEALink to PubMed article]
    Biological Process: cell adhesion [IEALink to PubMed article]
    Molecular Function: structural molecule activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSSNSVVPP FDARNLEIKT KSIEQTLIPL VTQITTLVNY KESYMASGKP KSERAMRAAL  60
   61 KIGSAVEAAI ERFVCVGETI ADENADIQPE MYDACTEARL AGASMANLSC ACNDDPNSVV 120
  121 DKAVLVRASR QLLSSVTRVL LLADRVLVKQ VLRAEDKIAF SLSRLESTRS FNDFVKVFAV 180
  181 FGGEMVELAH RSGDRQHDLK SEKRKAQMSI ARTSLERLTM LLLTASKTYL RHPDCDSALQ 240
  241 CRDGVFYQMK LSLELIAICV CDGILTTEKS RYIQDEPDMP IDIALQLTAN AAIKQLTEML 300
  301 EMIRMTVRVG AGVRERIVSA LDALCQLTQD FTDSAYTPHH QREQILDFLE ECRFEMTNLI 360
  361 QPDENEQLAA SGLEVTVERL NRRLKDLSKQ LQIVAMEQIS EVLRANEDQV LLSSMKACAV 420
  421 SGDIDGVEKY MHKFREHADH MQEVCRLLHH ISITDALHVH TGHVERNMRA LAPLTILAGR 480
  481 TLCVHPSSRI ARENLEVFCD TWGQAVNDLS RVAKESDVAA NGRVAAEKQA YMSLPRPGDQ 540
  541 QKMAKVGLEM KLLTSEVDAE AEKWDEYAEN DIVKRAKAMS SMAYNMYLFT RGDGPLKTTH 600
  601 DLFTQAEFFA EQANQMYRTV REFSYEVPGS AEKSDLSAIL ERIPLHCQQL QVMVKSPTVG 660
  661 KTATFGKVDS VIQETKNLMN EIAKLVTASF VCATKYEIEF RGGSVNGRTG ADGLAPDTKH 720
  721 PTSRAADLFA PFRQQLIKHT HLGQNAACFG LKPQKMRIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..631] PSI-BLAST 45.0 Crystal structure of a cytoskeletal protein
    2 View Details [632..759] PSI-BLAST 11.30103 Human vinculin head (1-258) in complex with human vinculin tail (879-1066)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.47862012796505 bayes_pls_golite062009
  • protein binding
    		•  2.02579891050608 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.07751635463993 bayes_pls_golite062009
  • cadherin binding
    		•  0.801778192092067 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle