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Protein Overview: CE30642

General Information:
Name(s) found: CE30642 [WormBase]
Description(s) found:
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  • WBGene00008455 Probable dimethyladenosine transferase status:Confirmed UniProt:Q09522 protein_id:CAA87382.2 [WormBase]
  • gi|27808654|sp|Q09522.2|DIMT1_CAEEL RecName: Full=Probable dimethyladenosine transferase; AltName: Full=S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; AltName: Full=18S rRNA dimethylase [NCBI NR]
  • gi|25146882|ref|NP_496061.2| hypothetical protein E02H1.1 [Caenorhabditis elegans] [NCBI NR]
  • gi|20803714|emb|CAA87382.2| C. elegans protein E02H1.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Probable dimethyladenosine transferase OS=Caenorhabditis elegans GN=E02H1.1 PE=2 SV=2 [Swiss-Prot]
  • (Q09522) Probable dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Swiss-Prot]
  • Probable dimethyladenosine transferase OS=Caenorhabditis elegans GN=E02H1.1 PE=3 SV=2 [Swiss-Prot]
  • [wormpep79.fasta]
  • CE30642 WBGene00008455 rRNA methyltransferase status:Confirmed SW:Q09522 protein_id:CAA87382.2 [wormpep150.fasta]
  • 30642 WBGene00008455 rRNA methyltransferase status:Confirmed SW:Q09522 protein_id:CAA87382.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • dimethyladenosine transferase (34.6 kD) (2J880) [Caenorhabditis elegans]gi|20803714|emb|CAA87382.2| Hypothetical protein E02H1.1 [Caenorhabditis elegans]gi|27808654|sp|Q09522|DIMI_CAEEL Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N [nrdb_11152004_Chlamydomonas]
  • rRNA methyltransferase status:Confirmed SW:Q09522 protein_id:CAA87382.2 [wormpep115.fasta.reversed]
  • CE30642 rRNA methyltransferase status:Confirmed SW:Q09522 protein_id:CAA87382.2 [wormpep80.hongbin]
  • CE30642 WBGene00008455 rRNA methyltransferase status:Confirmed UniProt:Q09522 protein_id:CAA87382.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30642 WBGene00008455 rRNA methyltransferase status:Confirmed UniProt:Q09522 protein_id:CAA87382.2| [wormORF-contam.fasta]
  • E02H1.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein E02H1.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30642 WBGene00008455 status:Confirmed UniProt:Q09522 protein_id:CAA87382.2 Probable dimethyladenosine transferase [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 308 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: rRNA modification [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    rRNA processing [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: rRNA methyltransferase activity [IEALink to PubMed article]
    rRNA (adenine) methyltransferase activity [IEALink to PubMed article]
    rRNA (adenine-N6,N6-)-dimethyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKTSKVKKT KAGSSTGNVQ SLPFNTDKGQ HILKNPGVVN AIVEKSALKA TDTVLEVGPG  60
   61 TGNLTVKMLE VAKTVIACEI DPRMIAEVKK RVMGTPLQNK LQVNGGDVMK MEWPFFDVCV 120
  121 ANLPYQISSP FVQKLLLHRP LPRYAVLMFQ KEFADRLVAR PGDKDYSRLS VNVQLLAKVE 180
  181 MLMKVKRTEF RPPPKVDSAV VRIAPKNPPP PVNFVEWEGL LRLCFMRKNK TLMAIFRLSN 240
  241 VIEVIEDNFR KVCSFKNKPI PKDLNMKKVI EETLTASGYG ESRARKMRVE DFLALLLAFN 300
  301 KADIHFLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] PSI-BLAST 70.045757 Crystal structure of human Dimethyladenosine transferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.00768472859991 bayes_pls_golite062009
  • methyltransferase activity
    		•  3.57681394097837 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.49392219433935 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  2.00108769169811 bayes_pls_golite062009
  • RNA binding
    		•  1.99752836873461 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.76571145896453 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.94499223839747 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • rRNA (uridine-2'-O-)-methyltransferase activity
    		•  0.90544396691236 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • binding
    		•  0.777596419415505 bayes_pls_golite062009
  • rRNA (uridine) methyltransferase activity
    		•  0.742142092552002 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • mRNA binding
    		•  0.0540207721800283 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.0408000230099101 bayes_pls_golite062009
  • snoRNA binding
    		•  0.00848192089639488 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle