Protein Overview: unc-2

General Information:
Name(s) found:	unc-2 / CE29459 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006742 locus:unc-2 status:Partially_confirmed UniProt:G5EFB0 protein_id:CCD74384.1 [WormBase] gi\|25146674\|ref\|NP_741734.1\| UNCoordinated family member (unc-2) [Caenorhabditis elegans] [NCBI NR] gi\|17976551\|gb\|AAB36868.3\| Uncoordinated protein 2, isoform a [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE29459 WBGene00006742 locus:unc-2 status:Partially_confirmed TR:Q22098 protein_id:AAB36868.3 [wormpep150.fasta] 29459 WBGene00006742 locus:unc-2 status:Partially_confirmed TR:Q22098 protein_id:AAB36868.3 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-2, voltage-gated Calcium Channel Alpha subunit (unc-2) [Caenorhabditis elegans]gi\|17976551\|gb\|AAB36868.3\| Uncoordinated protein 2, isoform a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:unc-2 status:Partially_confirmed TR:Q22098 protein_id:AAB36868.3 [wormpep115.fasta.reversed] CE29459 locus:unc-2 status:Partially_confirmed [wormpep80.hongbin] CE29459 WBGene00006742 locus:unc-2 status:Partially_confirmed UniProt:Q22098_CAEEL protein_id:AAB36868.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE29459 WBGene00006742 locus:unc-2 status:Partially_confirmed UniProt:Q22098_CAEEL protein_id:AAB36868.3\| [wormORF-contam.fasta] UNCoordinated family member (unc-2) [Caenorhabditis elegans] [nr-271106-contam.fasta] Uncoordinated protein 2, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta] CE29459 WBGene00006742 locus:unc-2 status:Partially_confirmed UniProt:Q22098 protein_id:AAB36868.3 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE29459 WBGene00006742 locus:unc-2 status:Partially_confirmed UniProt:G5EFB0 protein_id:CCD74384.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of G4SFC3, Uncharacterized protein OS=Caenorhabditis elegans GN=unc-2 PE=3 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1538 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	response to heat [IMP] ion transport [IEA] locomotory behavior [IMP] DNA methylation [IEA] regulation of neurotransmitter levels [IMP] response to starvation [IMP] negative regulation of transforming growth factor beta receptor signaling pathway [IGI]
Molecular Function:	DNA binding [IEA] ion channel activity [IEA] N-methyltransferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQHLPKNDK KALSEWLERT EPYFMGIFCL ECVLKVIAFG FALHKGSYLR SGWNIMDFIV  60
   61 VVSGVVTMLP FSPATQTANQ PVDSVDLRTL RAVRVLRPLK LVSGIPSLQV VLKSILCAMA 120
  121 PLLQIGLLVL FAIIIFAIIG LEFYSGAFHS ACYNERGEIE NVSERPMPCT NKTSPMGVYN 180
  181 CDVKGTTCLQ KWIGPNYGIT SFDNIGFAMI TVFQCITMEG WTTVMYYTND SLGSTYNWAY 240
  241 FIPLIVLGSF FMLNLVLGVL SGEFAKERER VENRREFLKL RRQQQIEREL NGYLEWILTA 300
  301 EEVILKEDRT TEEEKAAIME ARRRAANKKL KQASKQQSTE TEEDFEEDED EMEEEYVDEA 360
  361 ERKKRGCCHS VGKFIKQLRI QIRIMVKTQI FYWSVITLVF LNTCCVASEH YGQPQWFTDF 420
  421 LKYAEFVFLG IFVVEMLLKL FAMGSRTYFA SKFNRFDCVV IVGSAAEVIW AEVYGGSFGI 480
  481 SVMRALRLLR IFKLTSYWVS LRNLVRSLMN SMRSIISLLF LLFLFILIFA LLGMQLFGGR 540
  541 FNFPTMHPYT HFDTFPVALI TVFQVSKNVI NCKCINVLKI LTGEDWNEVM YLAIESQGGI 600
  601 YSGGWPYSIY FIVLVLFGNY TLLNVFLAIA VDNLANAQEL TAAEEADEKA NEIEEESEEL 660
  661 DEQYQEGDHC TIDMEGKTAG DMCAVARAMD DLDEECEEEE SPFGGPKPMV PYSSMFFLSP 720
  721 TNPFRVLIHS IVCTKYFEMM VMTVICLSSV SLAAEDPVDE ENPRNKVLQY MDYCFTGVFA 780
  781 CEMLLKLIDQ GILLHPGSYC RDFWNILDGI VVTCALFAFG FAGTEGSAGK NLNTIKSLRV 840
  841 LRVLRPLKTI KRIPKLKAVF DCVVNSLKNV FNILIVYFLF QFIFAVIAVQ LFNGKFFFCT 900
  901 DKNRKFANTC HGQFFVYDNQ NDPPRVEQRE WRLRPFNYDN TINAMLTLFV VTTGEGWPGI 960
  961 RQNSMDTTFE DQGPSPFFRV EVALFYVMFF IVFPFFFVNI FVALIIITFQ EQGEAELSEG1020
 1021 DLDKNQKQCI DFALNARPRS LFMPEDKNST KYRIWRLVTS PPFEYFIMTM ICCNTLILMM1080
 1081 KYYNNPLFYE EILRLFNTAL TAVFTVESIL KILAFGVRNY FRDGWNRFDF VTVVGSITDA1140
 1141 LVTEFGGHFV SLGFLRLFRA ARLIRLLQQG YTIRILLWTF VQSFKALPYV CLLIGMLFFI1200
 1201 YAIVGMQVFG NIWLNAATEI NRHNNFQSFF NAVILLFRCA TGEGWQDIMM AAVQGKDCAR1260
 1261 AGSAEINFEK GQTCGSNVSY AYFTSFVFLS SFLMLNLFVA VIMDNFDYLT RDSSILGPHH1320
 1321 LDEFIRVWAD YDPAATGRIH YSEMYEMLRI MAPPVGFGKK CPYRLAYKHL IRMNMPVAED1380
 1381 GTVHFTTTLF ALIRESLSIK MRPVEEMDEA DEELRLTLKK IWPLKAKKNM VDLVVPPNHE1440
 1441 LCFQKLTVGK IYAGLLILEN YRARKSGTER QSNDSVPPNF SENDEMRCST GFRKIPTSHR1500
 1501 SVDKDCLAEA YDRWSLQRKL PNRNILPTLH NRQRKPLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: unc-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: