Protein Overview: ncr-1

General Information:
Name(s) found:	ncr-1 / CE29251 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00003561 locus:ncr-1 Niemann-Pick C1 protein homolog 1 status:Partially_confirmed UniProt:Q19127 protein_id:CCD83387.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1383 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] late endosome [ISS] integral to membrane [IEA] lysosome [ISS]
Biological Process:	dauer larval development [IGI] regulation of oviposition [IMP] positive regulation of growth rate [IMP] embryonic development ending in birth or egg hatching [IMP] cholesterol transport [IEA] cholesterol homeostasis [IMP]
Molecular Function:	hedgehog receptor activity [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQLLIFCLL FGSIFHHGDA GCIMRGLCQK HTENAYGPCV TNDTNVEPTA FDKTHPAYEK  60
   61 MVEFCPHLLT GDNKLCCTPS QAEGLTKQIA QARHILGRCP SCFDNFAKLW CEFTCSPNQQ 120
  121 DFVSISEMKP IEKKEGFTPE YQPAEAYVNT VEYRLSTDFA EGMFSSCKDV TFGGQPALRV 180
  181 MCTSTPCTLT NWLEFIGTQN LDLNIPIHTK FLLYDPIKTP PSDRSTYMNV NFTGCDKSAR 240
  241 VGWPACSTSE CNKEEYANLI DLDDGKTSGQ TCNVHGIACL NIFVMLAFIG SLAVLLCVGF 300
  301 VFTSYDEDYT NLRQTQSGEE SPKRNRIKRT GAWIHNFMEN NARDIGMMAG RNPKSHFFIG 360
  361 CAVLIFCLPG MIYHKESTNV VDMWSSPRSR ARQEEMVFNA NFGRPQRYQQ IMLLSHRDFQ 420
  421 SSGKLYGPVF HKDIFEELFD ILNAIKNIST QDSDGRTITL DDVCYRPMGP GYDCLIMSPT 480
  481 NYFQGNKEHL DMKSNKEETV SEDDDAFDYF SSEATTDEWM NHMAACIDQP MSQKTKSGLS 540
  541 CMGTYGGPSA PNMVFGKNST NHQAANSIMM TILVTQRTEP EIQKAELWEK EFLKFCKEYR 600
  601 EKSPKVIFSF MAERSITDEI ENDAKDEIVT VVIALAFLIG YVTFSLGRYF VCENQLWSIL 660
  661 VHSRICLGML SVIINLLSSF CSWGIFSMFG IHPVKNALVV QFFVVTLLGV CRTFMVVKYY 720
  721 AQQRVSMPYM SPDQCPEIVG MVMAGTMPAM FSSSLGCAFS FFIGGFTDLP AIRTFCLYAG 780
  781 LAVLIDVVLH CTIFLALFVW DTQRELNGKP EFFFPYQIKD LLGAYLIGRQ RATDTFMTQF 840
  841 FHFQVAPFLM HRMTRIITGI IFIASFITTV ILSSKISVGF DQSMAFTEKS YISTHFRYLD 900
  901 KFFDVGPPVF FTVDGELDWH RPDVQNKFCT FPGCSDTSFG NIMNYAVGHT EQTYLSGEMY 960
  961 NWIDNYLEWI SRKSPCCKVY VHDPNTFCST NRNKSALDDK ACRTCMDFDY VANSYPKSSI1020
 1021 MYHRPSIEVF YRHLRHFLED TPNSECVFGG RASFKDAISF TSRGRIQASQ FMTFHKKLSI1080
 1081 SNSSDFIKAM DTARMVSRRL ERSIDDTAHV FAYSKIFPFY EQYSTIMPIL TTQLFITVVG1140
 1141 VFGIICVTLG IDVKGAACAV ICQVSNYFHI VAFMYIFNIP VNALSATNLV MSSGILIEFS1200
 1201 VNVLKGYACS LRQRAKDRAE STVGSIGPII LSGPVVTMAG STMFLSGAHL QIITVYFFKL1260
 1261 FLITIVSSAV HALIILPILL AFGGSRGHGS SETSTNDNDE QHDACVLSPT AESHISNVEE1320
 1321 GILNRPSLLD ASHILDPLLK AEGGIDKAID IITIDRSYPS TPSSLPCTSR MPRAHIEPDL1380
 1381 RSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ncr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: