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Protein Overview: CE29110

General Information:
Name(s) found: CE29110 [WormBase]
Description(s) found:
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  • WBGene00021534 locus:mvk-1 status:Partially_confirmed UniProt:Q9N4Z7 protein_id:CCD71154.1 [WormBase]
  • gi|71993790|ref|NP_001022866.1| hypothetical protein Y42G9A.4 [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_498328.1| mevalonate kinase (64.1 kD) (3H214) [Caenorhabditis elegans] [NCBI NR]
  • gi|15487591|gb|AAF60558.2| Hypothetical protein Y42G9A.4a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE29110 WBGene00021534 status:Partially_confirmed TR:Q9N4Z7 protein_id:AAF60558.2 [wormpep150.fasta]
  • 29110 WBGene00021534 status:Partially_confirmed TR:Q9N4Z7 protein_id:AAF60558.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • mevalonate kinase (64.1 kD) (3H214) [Caenorhabditis elegans]gi|15487591|gb|AAF60558.2| Hypothetical protein Y42G9A.4a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q9N4Z7 protein_id:AAF60558.2 [wormpep115.fasta.reversed]
  • CE29110 status:Partially_confirmed TR:Q9N4Z7 protein_id:AAF60558.2 [wormpep80.hongbin]
  • CE29110 WBGene00021534 status:Partially_confirmed UniProt:Q9N4Z7_CAEEL protein_id:AAF60558.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29110 WBGene00021534 status:Partially_confirmed UniProt:Q9N4Z7_CAEEL protein_id:AAF60558.2| [wormORF-contam.fasta]
  • Hypothetical protein Y42G9A.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Y42G9A.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE29110 WBGene00021534 status:Partially_confirmed UniProt:Q9N4Z7 protein_id:AAF60558.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29110 WBGene00021534 locus:mvk-1 status:Partially_confirmed UniProt:Q9N4Z7 protein_id:CCD71154.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q65XX9, MeValonate Kinase OS=Caenorhabditis elegans GN=mvk-1 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 607 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    phosphorylation [IEALink to PubMed article]
    isoprenoid biosynthetic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    mevalonate kinase activity [IEALink to PubMed article]
    kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVIGGDQAL DSPSGSTSRA GSSVSATASP MHRNTTSQHG GLFVSAPGKI ILFGEHAVVY  60
   61 GRTAIAGSID LRTYVSLYTS ADGRIYLSLP DLGVEKTWML KDLLKAADRL AAEYPIEEDQ 120
  121 PPSLEILVPI ARKLSGSCED QCGVQHLAIL AFWYLLLGVA HRKSGLSRLA RGLPAPPLPE 180
  181 GLHRTNLSVI GATSAQPEKS EAEIALSLPV PPLTPLPSPG AQSTAPPVFP TSTPTPTSTP 240
  241 TPLLPGNLRA DSPAVQQDLL AVKATVRFKL PSCVGLGSSG AYCVCIATSL LQTAGLIPPP 300
  301 SIVADEQGNL TWEEDHLDII RKWATAAESL IHGRASGLDA AVCTFGGVAS FKPGHRIEHL 360
  361 KNLPDLRVIL VNSKVERNTA RMVQTVKERL KKFPEVVDAM FGSIDAISLD AAKILHRPLL 420
  421 EENGGGDTGS TVQENGLGPF GGNMVEQDHH SLQPTRTASV RSSSLSSYVG GGKRNSSASV 480
  481 ISATSEKGEN VDTFSKLNDL CRINNQLLIA LGVGHPKVDL ICTTLARYGI HPKMTGAGGG 540
  541 GSVFAFLKPN TPQTLLDMID GELRSHGFEV WQPPLGGPGV VEHQTRPELF QTPVSSTQCS 600
  601 TPASKHK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] PSI-BLAST 5.221849 Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
    2 View Details [195..512] PSI-BLAST 40.221849 Mevalonate kinase
    3 View Details [513..607] FFAS03 2.81 x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.348396152404562 bayes_pls_golite062009
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.306083871041672 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle