Protein Overview: drsh-1

General Information:
Name(s) found:	drsh-1 / CE29039 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00009163 locus:drsh-1 Ribonuclease 3 status:Confirmed UniProt:O01326 protein_id:CAB03006.3 [WormBase] gi\|20141625\|sp\|O01326.2\|RNC_CAEEL RecName: Full=Ribonuclease 3; AltName: Full=Ribonuclease III; Short=RNase III; AltName: Full=Protein drosher [NCBI NR] gi\|17506883\|ref\|NP_492599.1\| Ortholog of Drosophila DRoSHa gene family member (drsh-1) [Caenorhabditis elegans] [NCBI NR] gi\|15718161\|emb\|CAB03006.3\| C. elegans protein F26E4.10a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] Ribonuclease 3 OS=Caenorhabditis elegans GN=drsh-1 PE=2 SV=2 [Swiss-Prot] [wormpep67.fasta] CE29039 WBGene00009163 locus:drsh-1 status:Partially_confirmed SW:O01326 protein_id:CAB03006.3 [wormpep150.fasta] 29039 WBGene00009163 locus:drsh-1 status:Partially_confirmed SW:O01326 protein_id:CAB03006.3 [wormpep130-phg-ecoli-orf-rand.fasta] ribonuclease similar to Drosophila drosha (1K358) [Caenorhabditis elegans]gi\|15718161\|emb\|CAB03006.3\| Hypothetical protein F26E4.10 [Caenorhabditis elegans]gi\|20141625\|sp\|O01326\|RNC_CAEEL Ribonuclease III (RNase III) [nrdb_11152004_Chlamydomonas] status:Partially_confirmed SW:O01326 protein_id:CAB03006.3 [wormpep115.fasta.reversed] CE29039 status:Partially_confirmed SW:O01326 protein_id:CAB03006.3 [wormpep80.hongbin] CE29039 WBGene00009163 locus:drsh-1 status:Partially_confirmed UniProt:RNC_CAEEL protein_id:CAB03006.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE29039 WBGene00009163 locus:drsh-1 status:Partially_confirmed UniProt:RNC_CAEEL protein_id:CAB03006.3\| [wormORF-contam.fasta] Hypothetical protein F26E4.10 [Caenorhabditis elegans] [nr-271106-contam.fasta] Ortholog of Drosophila DRoSHa gene family member (drsh-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Ribonuclease III (RNase III) [nr-271106-contam.fasta] CE29039 WBGene00009163 locus:drsh-1 status:Partially_confirmed UniProt:O01326 protein_id:CAB03006.3 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE29039 WBGene00009163 locus:drsh-1 status:Confirmed UniProt:O01326 protein_id:CAB03006.3 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE29039 WBGene00009163 locus:drsh-1 status:Confirmed UniProt:O01326 protein_id:CAB03006.3 Ribonuclease 3 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1086 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	embryonic cleavage [IMP] spindle organization [IMP] establishment of mitotic spindle orientation [IMP] embryonic development ending in birth or egg hatching [IMP ] rRNA catabolic process [IEA] cytokinesis [IMP] RNA processing [IEA]
Molecular Function:	RNA binding [IEA] ribonuclease III activity [IEA] double-stranded RNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEKISMTL NFPKHKRARR KKYQKEYQER HKEEMMQQLG RRFQNQPSTS SAPPDTVEKI  60
   61 PLPTESTSAL PFGDSPRLTE KDYETNYMID PPVVSTHSAE LIKSNRVVIK AEEAEKYMMI 120
  121 KAKSTTSKIL QDFQTKILET VKTKRRLQAD VPYIIHPCHS MKGRKTPKQK GGDESFTASD 180
  181 VSDDSNDSQD EASTSEPTNR QAPEADKTGE VKDEKQTCNR RNQQRKAKRL RNFEEKERQI 240
  241 TLLKKGIDRK KTHPNGIHPD ISFNEKGLGN EGPECRCPEP IKTCGLKHGY YAGEDKAIDC 300
  301 KKSNGENLHY YTLRVTPLPS ENQLYRTHMA INGEEFEFEG FSLITHAPLP DCMTRAPICK 360
  361 YSMDYEFQLV EEFMPDECFD PEDCDMLFEY IFHEIFEMLD FELRPKHIPS DVESCPMIHI 420
  421 MPRFVQTKDD LVQLWSSKTV LAYFTSKGSS EIMSPEDVNR LCDAQIDQFT RNTSKHKQSI 480
  481 VLNTKFKPSA IRADWFERDE EKKEVYVVHN AIRAQTYTAI SLPRIAFLEK TLNKMIQEKQ 540
  541 SSGVYNKDFE KTKNELEHLK RENRSARNLK LREPVAGFIE TGLKPDVAAH VVMTILACHH 600
  601 IRYNFSLDVF EEVIEYKFND RRVIELALMH SSFKSHYGTP IDHVKNMITN CGYRRKYGAE 660
  661 DKREKKRVAG IMSLFNIMKG TSGGEPILHN ERLEYLGDAV VELIVSHHLY FMLTHHFEGG 720
  721 LATYRTALVQ NRNLATLAKN CRIDEMLQYS HGADLINVAE FKHALANAFE AVMAAIYLDG 780
  781 GLAPCDVIFS KAMYGHQPVL KEKWDHINEH ELKREDPQGD RDLSFITPTL STFHALEERL 840
  841 GIQFNNIRLL AKAFTRRNIP NNDLTKGHNQ RLEWLGDSVL QLIVSDFLYR RFPYHHEGHM 900
  901 SLLRTSLVSN QTQAVVCDDL GFTEFVIKAP YKTPELKLKD KADLVEAFIG ALYVDRGIEH 960
  961 CRAFIRIVFC PRLKHFIESE KWNDAKSHLQ QWCLAMRDPS SSEPDMPEYR VLGIEGPTNN1020
 1021 RIFKIAVYYK GKRLASAAES NVHKAELRVA ELALANLESM SFSKMKAKNN SWFQNMRRRL1080
 1081 EQDTSD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: drsh-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: