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Protein Overview: unc-94

General Information:
Name(s) found: unc-94 / CE29023 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006823 locus:unc-94 Tropomodulin status:Confirmed UniProt:O01479 protein_id:CCD61217.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 392 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: tropomyosin binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQAKTDYYS EEKTFSAPSA NSQQGTQLPS KVYNKGLKDL EDNDIEGLLS SLSIDELEDL  60
   61 NNDFDPDNSM LPPSQRCRDQ TDKEPTGPYK RDNLLKFLED KAKTEKDWED VCPYTPGQKR 120
  121 GKVYDSDSGR NSEEPENGKM EMPIEIDLDD DEEELECALV TAPEKDLVDL AGILGMHNVL 180
  181 NQPQYYNALK GKTQDESTGT TFNGIMQSYV PRIVPDEPDN DTDVESCINR LREDDTDLKE 240
  241 VNINNMKRVS KERIRSLIEA ACNSKHIEKF SLANTAISDS EARGLIELIE TSPSLRVLNV 300
  301 ESNFLTPELL ARLLRSTLVT QSIVEFKADN QRQSVLGNQV EMDMMMAIEE NESLLRVGIS 360
  361 FASMEARHRV SEALERNYER VRLRRLGKDP NV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] Pfam 9.920819 No description for PF03250.5 was found. No confident structure predictions are available.
    2 View Details [203..392] PSI-BLAST 19.09691 Tropomodulin C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • microtubule minus-end binding
    		•  7.70887263207962 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  5.04595324782806 bayes_pls_golite062009
  • actin binding
    		•  4.98528043340021 bayes_pls_golite062009
  • tropomyosin binding
    		•  2.80631683562112 bayes_pls_golite062009
  • binding
    		•  2.665591019824 bayes_pls_golite062009
  • protein binding
    		•  2.66138763326419 bayes_pls_golite062009
  • myosin binding
    		•  1.32546860780591 bayes_pls_golite062009
  • tubulin binding
    		•  1.00494145757097 bayes_pls_golite062009
  • microtubule binding
    		•  0.854246295331667 bayes_pls_golite062009
  • catalytic activity
    		•  0.143741655309638 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  0.0986232864289136 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle