Protein Overview: ketn-1

General Information:
Name(s) found:	ketn-1 / CE28729 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00004130 locus:ketn-1 status:Confirmed UniProt:H2L074 protein_id:CCD71804.1 [WormBase] gi\|71995793\|ref\|NP_001023969.1\| KETtiN (Drosophila actin-binding) homolog family member (ketn-1) [Caenorhabditis elegans] [NCBI NR] gi\|15055359\|gb\|AAK82895.1\|AF106579_4 Kettin (drosophila actin-binding) homolog protein 1, isoform b [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] Prion-like-(q/n-rich)-domain-bearing protein protein 43, isoform b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] CE28729 WBGene00004130 locus:ketn-1 status:Confirmed TR:Q965G2 protein_id:AAK82895.1 [wormpep150.fasta] 28729 WBGene00004130 locus:pqn-43 status:Partially_confirmed TR:Q965G2 protein_id:AAK82895.1 [wormpep130-phg-ecoli-orf-rand.fasta] CE28729 WBGene00004130 locus:pqn-43 status:Partially_confirmed TR:Q965G2 protein_id:AAK82895.1 [wormpep132.fasta] 28729 WBGene00004130 locus:ketn-1 status:Confirmed TR:Q965G2 protein_id:AAK82895.1 [wormpep150-phg-orf-ecoli-rand.fasta] CE28729 WBGene00004130 locus:pqn-43 status:Confirmed TR:Q965G2 protein_id:AAK82895.1 [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta] locus:pqn-43 status:Partially_confirmed TR:Q965G2 protein_id:AAK82895.1 [wormpep115.fasta.reversed] CE28729 locus:pqn-43 status:Partially_confirmed [wormpep80.hongbin] CE28729 WBGene00004130 locus:ketn-1 status:Confirmed UniProt:Q965G2_CAEEL protein_id:AAK82895.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE28729 WBGene00004130 locus:ketn-1 status:Confirmed UniProt:Q965G2_CAEEL protein_id:AAK82895.1\| [wormORF-contam.fasta] Kettin (drosophila actin-binding) homolog protein 1, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta] KETtiN (Drosophila actin-binding) homolog family member (ketn-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE28729 WBGene00004130 locus:ketn-1 status:Confirmed UniProt:Q965G2 protein_id:AAK82895.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE28729 WBGene00004130 locus:ketn-1 status:Confirmed UniProt:H2L074 protein_id:CCD71804.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
Organism:	Caenorhabditis elegans
Length:	4203 amino acids
Gene Ontology:
Cellular Component:	extracellular region [IEA] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of cell growth [IEA] positive regulation of growth rate [IMP] cell adhesion [IEA] blood coagulation [IEA]
Molecular Function:	insulin-like growth factor binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHNFLKNLR KFRKNGGIKA ANGSAKTANG SANGSANGSA VHAANGGPSS QQARGHEHGA  60
   61 ALVNARPPQF LVHPQSVAAK AFETVTFSAK VVGTPTPSLT WQKSDGTVIQ SGGKYKIENG 120
  121 PDGSGRLIIE KVDAHDADMY MLVARNDGGS FQSSVDNKGN ETTLHINNAT MKEGGWYRCD 180
  181 ATNKHGTTTL KGRVVVNSRQ KFNGPAHREM ITLRKVDKVE RSRTPVNQLQ DVSASKSSPK 240
  241 FEGSLQSQQL VEGQSARLEI KYTPVEDPNL RIAWLLNGKG ILASSRIVTF TDFGIAALEI 300
  301 NPVNVFDQGE YTVVAVNPLG EARVSANIAV IGHGSFIQQQ QSGSQFGGTA YQSKGAQAPA 360
  361 GTHLDLPNFH SDLRSQEVFE GQQIHLETKL TPINDPDLRV VWLLDGNELP SNDKYRQTLS 420
  421 HGFASLDIPQ TSSNDSGLYS CRAFNKLGES ENQATIIIFA HSSQDLTPKF LSQIQPFHCE 480
  481 QELGRSFFEA RIQPINDPTL RVSWLKDGQP LPNANRIQIF QNFGVVSLSL HPTYPEDAGV 540
  541 YTCVLFNSHG QAQSSAELTT VWIDTLQLDS KHADSLPIIG YLDSHQIHIG PQSVERPEEF 600
  601 NSLEAPKFAR ELAGKIEVME NERVHFEARI LPANDVKMTV EWYHNGNPLP AAHRFHPMFD 660
  661 FGYVALDLLY AYPQDSGTYT LVARNELGEA RSNVELVVGT EKVLYLEPHH PEGLERIKEL 720
  721 EQDRRQGIAE VEDRTCDAAP KFLNDLPDIQ LNEHENIHVD LRATPVNDPT MVIEWFVNGR 780
  781 PLLTGSRVKT LNEFGFIALD IKGAIAEDSG TYSVRASNLL GEAIRQCVIT VTPAGQILSD 840
  841 TQHQESLGKI NYLENLNKYG RVEIEDKGPQ EPPTFVVPLQ ADLGDVEEGE PIHLECQVNP 900
  901 INDNSLKIIW LRDGQSLPHG HRFRTFYDFG FVSLDILGFY AQDAGTYTCR AENSLGQAET 960
  961 VATIRCAPKD AILGAVQHPR SYARIQEIEA PKPAPQEVPD LPHQPPAFVK QLGPAIQCME1020
 1021 GDNVYLEAQV TPTDDNSLTY EWLVNGQPLM KAHRFVLSQD FGYIALNILY CYPEDNGTYT1080
 1081 LVVRNRAGEA QSTVDINCGH TGGNFTDSFH PNSLHRIAEL ETPIQRAEPL PDKEKEVPTI1140
 1141 AKPLPATIDS VHESQTLHLE AQVTPIDDNT LRYEWLFNGN PLKASSRYRV LNDFGFVSLD1200
 1201 IDYIIAEDSG KYTLVVYNSA GRAETSCEFQ VDRLKSILSD TAHPESLRRI REMEQLQPAK1260
 1261 PSDDDAAAQP PVFTQQLTGP TEPLKEGQSV HMDCVVQPIN DPSLRIEWFH DGRPLMFGSR1320
 1321 IRTIHDFGYV GLEFLHIHPE DTGTYTCKAT NLIGEATTDI FLECKPRRNI YLDTHHESSW1380
 1381 QKIQEIENRV DEREPTPELT FQPPTFTENL ADKEDAQEGQ SIRLECRLIP VNDPTMRVTW1440
 1441 TRNGQPLPEA SRFMPARNFD YVNLDILALY GEDSGVYTCK AVSAFGEAAT SCTVKCAAGK1500
 1501 SLLLDTMHDA SWKRVQEIEN REKLEAVDAE PEKTAPKFVT QLNSSLGELQ EGVPIHLEAQ1560
 1561 VEPTNDNQLT VQWFHNGQPL ANGHRFRTRH DFGYVALDIL YAFAQDTGEW ACVARNSLGE1620
 1621 AQTIANFTVL PRGTIYTDSQ HPESWQKIQV LEAPRAAAPE KPDAEHDAPQ FIEPLDSIDR1680
 1681 MEFQSAHFQT KVTPQTDPNL RIQWFKDGQP LMNSNRFKLT TDFGYISLDI AHTVPEDSGV1740
 1741 YSVKASNAKG DAEVQAQLTV TGNAVILGDT QHEQSWQKIQ LIEAPRAPGE EEPDVKHGPP1800
 1801 KFVTQLHSLD GVVEGQPSHF EAQFIPFSDP KTSVQWYLNG NPLSASSRRI LRNDFGLVSL1860
 1861 DLQYTLGEDA GEYSVVVKNS EGEDRTSGQL SCTTRAAILG DTQHEQSWQR IQEIEAPRAP1920
 1921 GAEPEGPVYE KPSFVQPLQS VGDLPEGSVA LLEARLVPVN DPNLRVQWFY NDQPLMESNW1980
 1981 ISTSNDFGCV SLRIAPVYAR HTGVYSCKAW NDSGNAVTSA NVGVQGSEGL LLDTSHPASL2040
 2041 QKIQELEAID KYARLDAPER EYEKPQWVQG FENYENVGEG QTVTLHGLVE PSGDPHLRLE2100
 2101 WLLNGTPLRN ANRFRQEYEF GNAILTIVHV LPHDSGVYTC RAWNTQGEAS TSATVTTAGY2160
 2161 EKILYDSQHP VSWERIQELE APKIVEEIEE IVQKEKPNFL TQLESAENVP EGVPLHLEST2220
 2221 FQPARDPELK VVWQKNGQPL GASQLVQTKH ELGWATLDIS SANEDHNGVY TLTITNSEGE2280
 2281 AVSTASIRVA GTGPILGNTR HEESWKRIQI LEAPKEAEPE APAPVYDHPA ITTQIDDKEC2340
 2341 NEGDHVHFEA LITPVNDPRL QVQWIRNGVP LAHGSKYAIQ QDFGICTLDV AYTYPEDEGV2400
 2401 YQLRIWNPEG EAVSSATLKC HGKDAILGDV QHQESWKRIQ EIEAPKQKLE EADPEPKGPP2460
 2461 RFIQQLTSPG SLVENQPAHF EATVEPVDDP TLTINWFLNG EPMSASSRVK MINDFGWVIM2520
 2521 DIAQTEPRDS GEWKCVAKNA AGEAVSTATI EVQGKEVILQ DSLQPQSLDR IRQIEAGKPA2580
 2581 PEERPDQQFE APAIVNALQV QGALEEGGSA HLQTQFTPVA DPSIKVEWLK DGQPIFHSNR2640
 2641 YKMVHDFGFA VLDILHLLKH DAGEYTFRVS NNSGEASTST SFEVSESSGL ILQPQNEQKA2700
 2701 KAVEILEDNL RRRPEEIEQE LKEATPVFIE PLSAPVETEE GGRAHFTARY EPVNDNQLQV2760
 2761 QWYHDGRPLK NGSRIKTINS FGYVVLEISP TYPEDNGEYI CRAVNRVGEA VTSTKLTCTP2820
 2821 KEGIISATQL PERMANAGRR IAEIEAPRPA REDAPDADHG PPKFTSALAG PPELQEGQQA2880
 2881 HLECQVTPVA DPRLVIEWFH NGQPVNHTNR MKAIHDFGFV VLQLTPAEPQ DSGTWTCRAT2940
 2941 NQHGSDEVST ELKVVGGGGV SYEWQSTAER KERITELEDW IHRPKEDLNL PAVDYPAPSF3000
 3001 SQGLTDLGQL NEADATAFVC VLEPIGDPTL RVQWEHNGHP IPYSNRISCT NEFGVATLLI3060
 3061 KHLIAADAGE YKCVATNVKG SATSVGKIAV ESSTQIDAPQ VVQQLVDSVE NILEGDSIHL3120
 3121 ECRVTPINDP RLHVEWLRNG APLPEASRFK PTFEFGFVSL DILYAYPEDN GDYELVVRND3180
 3181 KGEARSKTKI TVLPRPSLDY TSQTHGNQQD SLESHFKQHS QAKLQLTAND IYNESDKRAP3240
 3241 EFRTQLQNIG VLEGEFCRFE TQVAPINDPY LKVEWFKDKK PVLLGHRFRS TLDFGFACLD3300
 3301 LLYALPDDTG EYHCVATNRH GQTMISAKLA CQGASHVITD SQMPQGLRVS NVKKDNKNIY3360
 3361 WSEQGGAVQP KQKQAPQFTI PLRNLQVTEN QPARFECAVT GYPRPKVTWF INGNQCLHGH3420
 3421 RFKLNFDGLH YLTVSKSRIS DAGEVVAIAR NTEGETISTA TLDIFQNDDF RQTKLRPANF3480
 3481 KTSDELRERE LQWQRDTLGS LGPAFEAAPK PDAQKLMHVE RAQSPIEPME SQELIQKFTR3540
 3541 PRDDNFYNKL SYVELQKPQF KGMELEEVNL KAGKVEKYQP PVEEMERVNL KAIPEKDQQE3600
 3601 VGWERPDWAG QDGTSKLPGA DEGRFKKLPT PAPELDVPAR DQVKLKTAKP TRGKDLEAGE3660
 3661 KVKLKTEKAK IKEIQQKPEQ PKEEPIVHKD AVQLKTQQLP KTGIKGDHFT VDREKDLKET3720
 3721 PAVVKPVIEE TRISNKVYLS VETADSFSQV QRLEYSPRSP RRERIIGFHM IRPQPTKIGQ3780
 3781 SKQAPPTISQ QLKPLQGELG KAAKFVIEFA GAAPVKVTWL KDGKEIKSTF RTLITTTPTN3840
 3841 SSLHIGRLEN SHAGEYTVRL ENAAGTVESL ANLTVAPPTT QGKAPDFSAR LNDLRIQQNG3900
 3901 PAEFSCQIGG EPKPTIQWFK DGQPLPNDDR FQVVEEGGAY KLKFSNIIST DAGIYEIVAK3960
 3961 NGVGEARCKA RLNVNLQKTG KGAEEGPRYE APRFTSQIQP IVVDEGKGAQ FSAQFSGFPD4020
 4021 PTIRWYRNNE PVKHADGYEI SQSKGEAILR ISAARNEDVA EYKVEASNPA GKASSVANLV4080
 4081 LTPRSGRIAK STISRGGSAS YQSSDKAAAD SPHFIAKLSD ISARQGHTVK FSAEVDGNPE4140
 4141 PTVQWQFKGK PISASNNVKI SRDGKRAILE LARVTPDSAG EYQIVIRNDK GAATSQAKLT4200
 4201 LSA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: ketn-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: