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Protein Overview: exo-1

General Information:
Name(s) found: exo-1 / CE28728 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00009731 locus:exo-1 status:Confirmed UniProt:O62245 protein_id:CAB07612.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [IEALink to PubMed article]
    Molecular Function: nuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGISGLLPFV KNACRKGNIL ELRGKSVAID VSCLLHRGLT GCMDKIHMGE ETQSYVNYVN  60
   61 KYVKELLGMG CHVVMVFDGR PLPAKKGTNE ERRELREKRK EHAEMLLAKG LEREARDTYR 120
  121 LATSISADIV ENTIQYFRSM TNVDIVVAPY EADAQLAYLV QEKLVDAVIT EDSDLIVFGC 180
  181 EMIYFKWQSA TGECSVYEKC NLKNCFTGEL GGDKFDFVKF RRICILSGCD YLQAGLPGVG 240
  241 LSTAAKFFSM TSIKDLRTLL RKVPSYLKNP KLKEHVNDEF IRNFEKAENT FKHQIVFDPR 300
  301 ERCQKPLTPY PKEVLMTGVD DLEEVIDLDS PKKTAPSSKS FAYAGTASTQ RIAIRLALGN 360
  361 PENKSSIDDQ FLLVQPTPEW SVWGLRYESK GSTLDKISKQ KELEATQCGG AFKLDSPSVK 420
  421 RVKVASKTTP NDDEDDIVKQ FMADIEKEKK AIKKRKNAPQ VDYNADVLLK KYAEPPPEKR 480
  481 QKILEVIDDD FSEFFQEKVK ENTKESVAEE KVENSNEELK PPPILRKAVS TPDSARKTHK 540
  541 FQSPLLNHQN SAPPSLPDRK PAQTSKYFSK PTSENGVPKT KNPFRCPAFV KPTQKVEEKI 600
  601 EKTTILAALE ENSVPMPSSN TTYRFVGFKS AGLRRKSKQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 62.221849 Crystal structure of the human FEN1-PCNA complex
    2 View Details [375..479] deduced N/A No confident structure predictions are available.
    3 View Details [480..639] MSA 11.203997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.845290320008287 bayes_pls_golite062009
  • hydrolase activity
    		•  0.31554871338907 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.12799711467808 bayes_pls_golite062009
  • nuclease activity
    		•  0.0878151841480506 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle