Protein Overview: unc-26

General Information:
Name(s) found:	unc-26 / CE28239 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006763 locus:unc-26 status:Confirmed UniProt:G5EEJ9 protein_id:CAB05234.2 [WormBase] gi\|71990653\|ref\|NP_001023265.1\| UNCoordinated family member (unc-26) [Caenorhabditis elegans] [NCBI NR] ref\|NP_741495.1\| UNCoordinated locomotion UNC-26, synaptojanin (123.4 kD) (unc-26) [Caenorhabditis elegans] [NCBI NR] gi\|14787744\|emb\|CAC44311.1\| C. elegans protein JC8.10a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|14530486\|emb\|CAB05234.2\| C. elegans protein JC8.10a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|10567759\|gb\|AAG18575.1\|AF283323_1 synaptojanin UNC-26B [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed TR:Q9XUD3 protein_id:CAC44311.1 [wormpep150.fasta] 28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed TR:Q9XUD3 protein_id:CAC44311.1 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-26, synaptojanin (123.4 kD) (unc-26) [Caenorhabditis elegans]gi\|14787744\|emb\|CAC44311.1\| Hypothetical protein JC8.10a [Caenorhabditis elegans]gi\|14530486\|emb\|CAB05234.2\| Hypothetical protein JC8.10a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed TR:Q9XUD3 protein_id:CAC44311.1 [wormpep115.fasta.reversed] CE28239 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed TR:Q9XUD3 protein_id:CAC44311.1 [wormpep80.hongbin] CE28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed UniProt:Q9XUD3_CAEEL protein_id:CAC44311.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed UniProt:Q9XUD3_CAEEL protein_id:CAC44311.1\| [wormORF-contam.fasta] Hypothetical protein JC8.10a [Caenorhabditis elegans] [nr-271106-contam.fasta] synaptojanin UNC-26B [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-26) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed UniProt:Q9XUD3 protein_id:CAC44311.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE28239 WBGene00006763 locus:unc-26 Inositol polyphosphate phosphatase, catalytic domain homologues status:Confirmed UniProt:G5EEJ9 protein_id:CAB05234.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE28239 WBGene00006763 locus:unc-26 status:Confirmed UniProt:G5EEJ9 protein_id:CAB05234.2 [wormpep246-ecoli-contam.fasta] Isoform of G5ECL2, Synaptojanin UNC-26B OS=Caenorhabditis elegans GN=unc-26 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1113 amino acids
Gene Ontology:
Cellular Component:	synaptic vesicle [ISS]
Biological Process:	cytoskeleton organization [IMP] acetylcholine transport [IMP] endosome organization [IMP] locomotion [IMP] regulation of forward locomotion [IMP] regulation of backward locomotion [IMP] positive regulation of muscle contraction [IMP] positive regulation of multicellular organism growth [IMP] synaptic vesicle uncoating [IMP] locomotory behavior [IMP] synaptic vesicle transport [IMP] vesicle organization [IMP] synaptic vesicle endocytosis [IMP] muscle contraction [IMP] Golgi vesicle uncoating [IMP] synaptic vesicle budding from presynaptic membrane [IMP] positive regulation of neurotransmitter secretion [IMP] gamma-aminobutyric acid transport [IMP]
Molecular Function:	inositol or phosphatidylinositol phosphatase activity [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRGIRIWR RNDARFQPSI LVEKNGLDGS LLFQGGAIAT LDSDSTDVER RSYQKIVDAY  60
   61 GILGVLAITK DEAVLVAVTG VLSVGQLYGA DILKITNVEF ISLRTFGSVE NVDSRIIDLQ 120
  121 RLLSSQMFYF SSLQSYDLTR SAQHRDSHDC SDARFFWNRS LHFSFQRYGI DTDNWLLKCM 180
  181 AGSVLVRVVY VGANTGRVAL ISRLSCERVG TRFNVRGANY LGNVANFVET EQLLLFDEKE 240
  241 CSLLQIRGSI PLFWEQPGVN VGSHKVKLRA FETSLPAYHR HLSQLQHRYG EFAIVNLLGR 300
  301 KEGERVLGDA FKTQHKSSHF APLVDFIDFD YHAQMKISKE AIVQLKKKMS PHMTKHGFFY 360
  361 SMGKEIVKRQ TGVIRTNCLD CLDRTNAVQT AIGLQMSHDQ VAFLNLNAGK VNVEQRVEEI 420
  421 LRDLWQKNGD QCSTIYAGTG ALDGKSKLKD ASRSLARTIQ NNLMDGAKQE SFDLFLTGAA 480
  481 YDPRLFDRAC NILPPSLIQE YADAVSQLVE RSPEIAEPQS IKIFVGTWNV NGGKNIHNVA 540
  541 FRNESSLSHW IFANSMTRLV SVEDEQLADI VAIGVEELVD LNASNMVKAS TTNQRMWCES 600
  601 IRKTLSEKAP FVLIGSEQLV GVCLFLFARP RVSPYLKDFA VASVKTGMGG ATGNKGSVAF 660
  661 RIVVFSTSIC FICSHFAAGQ NEIRDRNEDF ATTLKKIRFP LGREIDSHDV IFWLGDFNYR 720
  721 INLSGDEVKN AVRNGDYAKL VENDQLTQQK ALGQTFVGFN EGQLTFAPTY KYDTFSDDYD 780
  781 TSEKCRAPAW TDRILWKDQR KKGKTQLLSY DRSELKTSDH RPVGAVFKVE TFKVGGRKCV 840
  841 ELIEDVVESM GPPDGTIIVS IAGKPRFPPQ MFPPIHEKLK ELGAQVQLSK FDDGDLWIVL 900
  901 NSGEMALAAL SMDGLKIGGT DQINVKLKSP DWAYALKPHL SDFDLESFEV TAEEEALLGG 960
  961 TDGAVFEFAD EDEDAISVSS LTLTGSAPDR PRPPSARSEA ISVAKLEWPT EQPNVLSTSM1020
 1021 PTRASSASLA NSSWYEHVPP LAPPQSNNNK SPPQACLFNP FTQSAPSPAP PPSTIPLPPT1080
 1081 RGASVGPGPP AVPVRKAPPP PPRPVIPPRP KNM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.69

Protein Overview: unc-26

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: