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The directed movement of substances in synaptic membrane-bounded vesicles within the neuron along the cytoskeleton either toward or away from the neuronal cell body. Invagination of the axonal plasma membrane creating a membrane-bounded vesicle. Without this process the presynaptic terminal would swell up due to fusion of vesicle membranes during neurotransmitter release. The vesicles created may subsequently be used for neurotransmitter storage/release. The process by which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. The removal of the protein coat on a synaptic vesicle. A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle. The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: synaptic vesicle uncoating
Acc: GO:0016191
Aspect: Biological Process
Desc: The removal of the protein coat on a synaptic vesicle.
Synonyms:
  • synaptic vesicle coat protein depolymerization
  • synaptic vesicle coat depolymerization
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016191 - synaptic vesicle uncoating (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle