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Protein Overview: mdf-1

General Information:
Name(s) found: mdf-1 / CE28212 [WormBase]
Description(s) found:
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  • WBGene00003160 locus:mdf-1 status:Confirmed UniProt:G5EFM0 protein_id:CAA94745.2 [WormBase]
  • gi|7542553|gb|AAF63494.1|AF239998_1 MDF-1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17558802|ref|NP_505462.1| MAD (yeast Mitosis Arrest DeFicient) related family member (mdf-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530364|emb|CAA94745.2| C. elegans protein C50F4.11, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE28212 WBGene00003160 locus:mdf-1 status:Confirmed TR:Q9NGT4 protein_id:CAA94745.2 [wormpep150.fasta]
  • 28212 WBGene00003160 locus:mdf-1 status:Confirmed TR:Q9NGT4 protein_id:CAA94745.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • yeast Mitosis Arrest DeFicient related, component of the spindle-assembly checkpoint MDF-1, binds to Mitosis arrest DeFicient MDF-2 (78.6 kD) (mdf-1) [Caenorhabditis elegans]gi|14530364|emb|CAA94745.2| Hypothetical protein C50F4.11 [Caenorhabditis elegan [nrdb_11152004_Chlamydomonas]
  • locus:mdf-1 status:Confirmed TR:Q9NGT4 protein_id:CAA94745.2 [wormpep115.fasta.reversed]
  • CE28212 status:Confirmed TR:Q9NGT4 protein_id:CAA94745.2 [wormpep80.hongbin]
  • CE28212 WBGene00003160 locus:mdf-1 status:Confirmed UniProt:Q9NGT4_CAEEL protein_id:CAA94745.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28212 WBGene00003160 locus:mdf-1 status:Confirmed UniProt:Q9NGT4_CAEEL protein_id:CAA94745.2| [wormORF-contam.fasta]
  • MAD (yeast Mitosis Arrest DeFicient) related family member (mdf-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C50F4.11 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • MDF-1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE28212 WBGene00003160 locus:mdf-1 status:Confirmed UniProt:Q9NGT4 protein_id:CAA94745.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28212 WBGene00003160 locus:mdf-1 status:Confirmed UniProt:G5EFM0 protein_id:CAA94745.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • MAD (Yeast Mitosis arrest DeFicient) related OS=Caenorhabditis elegans GN=mdf-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 679 amino acids

    Gene Ontology:
    Cellular Component: kinetochore [IDA]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYDEDIVDE DEYEESEATM LFAEEIKKQF KREFPLKAET EKKLKQATFR RHAPVEARKI  60
   61 NFDMTLSPVA PIELASAKKE KESAQRQLVT LREDHERMKQ MMQTNQAKLA EKTIDLETNR 120
  121 EKMLELQEQV ELLKQERDDT IAECNRNVDI WTAFGKKYYT WYSMANTQLE SVKLYIDNDG 180
  181 KFENDEEVTR LNAVPRQMYR ALEQFDYDDE TVEELGSGSL LEYEGVSFAT RRPPSPETER 240
  241 EIARADQSAA NFTLPQSNFT LLEDSNNTIM PEDQTMMTDG CIANRSLIDY EKDEKIQRLL 300
  301 LENSVLKDRL NVSSGRAERS MIFEERNRTL EFEKKALHKQ LDSTFSEIEA IRIGQAGNLF 360
  361 NIDEKIPSSS DNSAKQLQLI DRITQLITKN NQLEKDFEAA TSRMTKVMRE STDCARRNER 420
  421 LEDAFSSERV RSQDLENEKS RLSEQLELSN NELEKVKKQL EESQSQLDEV LSMTLTVPAS 480
  481 EPASLPAPTD AGNSTQIFHM ASNPLQDAHN EFQASESRKR KLTDAPAGDQ WREQEFAELE 540
  541 KRLYDCESEK KVLESSYNLH KELSSKFRQV CIALTGLQIK LKDADEGICT VQSEYEGGSA 600
  601 QQFVFKYFYG TPRIDMLDVS CESTTEMLRK WEPLMKKYIG DRNSIPAFLA AMTLQLEQDR 660
  661 DFDETMHERT HTFSVLHED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..192] deduced N/A No confident structure predictions are available.
    2 View Details [193..538] PSI-BLAST 17.0 Heavy meromyosin subfragment
    3 View Details [539..679] PSI-BLAST 11.0 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle