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View Structure Prediction Details

Protein: mdf-1
Organism: Caenorhabditis elegans
Length: 679 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mdf-1.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
253.0 [0..4] [678..2072]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYDEDIVDE DEYEESEATM LFAEEIKKQF KREFPLKAET EKKLKQATFR RHAPVEARKI  60
   61 NFDMTLSPVA PIELASAKKE KESAQRQLVT LREDHERMKQ MMQTNQAKLA EKTIDLETNR 120
  121 EKMLELQEQV ELLKQERDDT IAECNRNVDI WTAFGKKYYT WYSMANTQLE SVKLYIDNDG 180
  181 KFENDEEVTR LN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [193-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVPRQMYRAL EQFDYDDETV EELGSGSLLE YEGVSFATRR PPSPETEREI ARADQSAANF  60
   61 TLPQSNFTLL EDSNNTIMPE DQTMMTDGCI ANRSLIDYEK DEKIQRLLLE NSVLKDRLNV 120
  121 SSGRAERSMI FEERNRTLEF EKKALHKQLD STFSEIEAIR IGQAGNLFNI DEKIPSSSDN 180
  181 SAKQLQLIDR ITQLITKNNQ LEKDFEAATS RMTKVMREST DCARRNERLE DAFSSERVRS 240
  241 QDLENEKSRL SEQLELSNNE LEKVKKQLEE SQSQLDEVLS MTLTVPASEP ASLPAPTDAG 300
  301 NSTQIFHMAS NPLQDAHNEF QASESRKRKL TDAPAGDQWR EQEFAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [539-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEKRLYDCES EKKVLESSYN LHKELSSKFR QVCIALTGLQ IKLKDADEGI CTVQSEYEGG  60
   61 SAQQFVFKYF YGTPRIDMLD VSCESTTEML RKWEPLMKKY IGDRNSIPAF LAAMTLQLEQ 120
  121 DRDFDETMHE RTHTFSVLHE D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle