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Protein Overview: pie-1

General Information:
Name(s) found: pie-1 / CE28134 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00004027 locus:pie-1 Pharynx and intestine in excess protein 1 status:Confirmed UniProt:Q94131 protein_id:CAB11564.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 335 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    centrosome [IDALink to PubMed article]
    P granule [IDALink to PubMed article]
    Biological Process: negative regulation of transcription [IMPLink to PubMed article]
    embryonic pattern specification [IGILink to PubMed article][IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    formation of primary germ layer [IMPLink to PubMed article]
    cell fate determination [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    general transcriptional repressor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQTKPIAEQ MAALNNSDDT SFAADRSNSL LNATCPARIQ NSVDQRKINR SFNDSLSSGY  60
   61 SGKWLRPKRE ALKITPLAQI DEAPATKRHS SAKDKHTEYK TRLCDAFRRE GYCPYNDNCT 120
  121 YAHGQDELRV PRRRQEYYSR DPPRERRDSR SRRDDVDTTI NRSSSSASKH HDENRRPSNN 180
  181 HGSSNRRQIC HNFERGNCRY GPRCRFIHVE QMQHFNANAT VYAPPSSDCP PPIAYYHHHP 240
  241 QHQQQFLPFP MPYFLAPPPQ AQQGAPFPVQ YIPQQHDLMN SQPMYAPMAP TYYYQPINSN 300
  301 GMPMMDVTID PNATGGAFEV FPDGFFSQPP PTIIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] deduced N/A No confident structure predictions are available.
    2 View Details [89..154] PSI-BLAST 13.69897 Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d
    3 View Details [155..223] FFAS03 2.2 No description for 2e5sA was found.
    4 View Details [224..335] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle