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Protein Overview: obr-1

General Information:
Name(s) found: obr-1 / CE28126 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00012930 locus:obr-1 Oxysterol-binding protein status:Partially_confirmed UniProt:Q95Q23 protein_id:CAC42376.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 627 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    steroid metabolic process [IEALink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRQQWTNSL EYMRHKAITR AESEEDEDAQ MAKTDSNRSD ALILANRQMS GKLCDLRTAA  60
   61 NMMNKQGDEL MRALNGTVET DKNSLAERAD LLKMTTSAVL QAAEEFVELS EQSAKRLNKI 120
  121 VAVEQKEKAL LQEQLEALAK QHSSLERAAS KCARGAAPVS VYSDQEDDEF HDAEEDLAMP 180
  181 CSNSNGPPAT AGVHLTPTKR HIGAGDPSSS TCSDSGAVVV VGAHKGGRQR RTTVPERPNL 240
  241 PINLWSIMKN CIGKELSKIP MPVNFSEPIS VLQRVTEDLE YANLLETGAK LSTLEQMCYV 300
  301 AAYAASNYST TCHRTNKPFN PLLGETFEFD RMDDLGWRSV TEQVSHHPPA AAHHAEGNGW 360
  361 TMYQDFTMTS RFRGKYLSVI PIGFTHVVFP ATKSHFSYRK ITTTVHNIIV GKLWIDNHGD 420
  421 MEITNHETNE KCLLKFVPYS YFSREQPRKV YGIVRDAEGI PKYVVQGTWD KSIDMLKVSS 480
  481 WNGNHEKPKL EVDETSLKRI WTANPLPKNA EKMHNFTKLA IELNEPEEGV APTDSRLRPD 540
  541 QRLMENGEWD EANRKKLEIE EKQRVVRRRR EAEKELAMKK GDKYEEYEPT WFVRVQDESN 600
  601 GALIHQFKGG YWEAKEQQNW EKCPDIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] FFAS03 1.05 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    2 View Details [233..627] PSI-BLAST 65.30103 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle