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View Structure Prediction Details

Protein: obr-1
Organism: Caenorhabditis elegans
Length: 627 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for obr-1.

Description E-value Query
Range
Subject
Range
gi|168985196, gi... - gi|168985196|emb|CAQ07893.1| oxysterol binding protein 2 [Homo sapiens], gi|168984183|emb|CAQ07397.1...
628.0 [0..1] [627..260]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRQQWTNSL EYMRHKAITR AESEEDEDAQ MAKTDSNRSD ALILANRQMS GKLCDLRTAA  60
   61 NMMNKQGDEL MRALNGTVET DKNSLAERAD LLKMTTSAVL QAAEEFVELS EQSAKRLNKI 120
  121 VAVEQKEKAL LQEQLEALAK QHSSLERAAS KCARGAAPVS VYSDQEDDEF HDAEEDLAMP 180
  181 CSNSNGPPAT AGVHLTPTKR HIGAGDPSSS TCSDSGAVVV VGAHKGGRQR RT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [233-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVPERPNLPI NLWSIMKNCI GKELSKIPMP VNFSEPISVL QRVTEDLEYA NLLETGAKLS  60
   61 TLEQMCYVAA YAASNYSTTC HRTNKPFNPL LGETFEFDRM DDLGWRSVTE QVSHHPPAAA 120
  121 HHAEGNGWTM YQDFTMTSRF RGKYLSVIPI GFTHVVFPAT KSHFSYRKIT TTVHNIIVGK 180
  181 LWIDNHGDME ITNHETNEKC LLKFVPYSYF SREQPRKVYG IVRDAEGIPK YVVQGTWDKS 240
  241 IDMLKVSSWN GNHEKPKLEV DETSLKRIWT ANPLPKNAEK MHNFTKLAIE LNEPEEGVAP 300
  301 TDSRLRPDQR LMENGEWDEA NRKKLEIEEK QRVVRRRREA EKELAMKKGD KYEEYEPTWF 360
  361 VRVQDESNGA LIHQFKGGYW EAKEQQNWEK CPDIF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.30103
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle