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Protein Overview: par-6

General Information:
Name(s) found: par-6 / CE28089 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00003921 locus:par-6 Partitioning defective protein 6 status:Confirmed UniProt:Q9NAN2 protein_id:CAB61018.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 309 amino acids

    Gene Ontology:
    Cellular Component: cell cortex [IDALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    establishment of mitotic spindle localization [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYNGSYHQN HHSTLQVKSK FDSEWRRFSI PMHSASGVSY DGFRSLVEKL HHLESVQFTL  60
   61 CYNSTGGDLL PITNDDNLRK SFESARPLLR LLIQRRGESW EEKYGYGTDS DKRWKGISSL 120
  121 MAQKPPKRSY SISNPEDFRQ VSAIIDVDIV PEAHRRVRLC KHGQERPLGF YIRDGTSVRV 180
  181 TERGVVKVSG IFISRLVDGG LAESTGLLGV NDEVLEVNGI EVLGKTLDQV TDMMVANAHN 240
  241 LIITVKPANQ RNTLSRGPSQ QGTPNASEMS AATAAATGGI QRPMKMNGSS DGSYHPKQHD 300
  301 ANDSDSGED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] PSI-BLAST 13.154902 Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha
    2 View Details [120..309] PSI-BLAST 27.39794 GTPase-binding domain of the cell polarity protein par6 (Par-6B)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.40375748362287 bayes_pls_golite062009
  • protein binding
    		•  0.945681812802111 bayes_pls_golite062009
  • signal transducer activity
    		•  0.706760857353951 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.706760857353951 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.4211406884996 bayes_pls_golite062009
  • protein binding
    		•  2.25893018754605 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.21190589781988 bayes_pls_golite062009
  • transporter activity
    		•  1.14862709059264 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.03502943752333 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.724101421194961 bayes_pls_golite062009
  • signal transducer activity
    		•  0.521000883356655 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.521000883356655 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.520243659117793 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.221504678128513 bayes_pls_golite062009
  • receptor binding
    		•  0.134267863083984 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle