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View Structure Prediction Details

Protein: par-6
Organism: Caenorhabditis elegans
Length: 309 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for par-6.

Description E-value Query
Range
Subject
Range
gi|7508501 - gi|7508501|pir||T25297 hypothetical protein T26E3.3 - Caenorhabditis elegans
222.0 [0..1] [309..1]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYNGSYHQN HHSTLQVKSK FDSEWRRFSI PMHSASGVSY DGFRSLVEKL HHLESVQFTL  60
   61 CYNSTGGDLL PITNDDNLRK SFESARPLLR LLIQRRGESW EEKYGYGTDS DKRWKGISS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1wmhB
Description: Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.40375748362287 bayes_pls_golite062009
protein binding 0.945681812802111 bayes_pls_golite062009
signal transducer activity 0.706760857353951 bayes_pls_golite062009
molecular transducer activity 0.706760857353951 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [120-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMAQKPPKRS YSISNPEDFR QVSAIIDVDI VPEAHRRVRL CKHGQERPLG FYIRDGTSVR  60
   61 VTERGVVKVS GIFISRLVDG GLAESTGLLG VNDEVLEVNG IEVLGKTLDQ VTDMMVANAH 120
  121 NLIITVKPAN QRNTLSRGPS QQGTPNASEM SAATAAATGG IQRPMKMNGS SDGSYHPKQH 180
  181 DANDSDSGED 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 1nf3C
Description: GTPase-binding domain of the cell polarity protein par6 (Par-6B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.4211406884996 bayes_pls_golite062009
protein binding 2.25893018754605 bayes_pls_golite062009
cytoskeletal protein binding 1.21190589781988 bayes_pls_golite062009
transporter activity 1.14862709059264 bayes_pls_golite062009
transmembrane transporter activity 1.03502943752333 bayes_pls_golite062009
substrate-specific transporter activity 0.724101421194961 bayes_pls_golite062009
signal transducer activity 0.521000883356655 bayes_pls_golite062009
molecular transducer activity 0.521000883356655 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.520243659117793 bayes_pls_golite062009
active transmembrane transporter activity 0.221504678128513 bayes_pls_golite062009
receptor binding 0.134267863083984 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle