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Protein Overview: unc-49

General Information:
Name(s) found: unc-49 / CE28086 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006784 locus:unc-49 status:Confirmed UniProt:G5EE10 protein_id:CAC42350.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 448 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    regulation of backward locomotion [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    gamma-aminobutyric acid signaling pathway [IMPLink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPFTLIVL LSAHLCLHVV VTQDEDSHIN TQLLSSVLDR LTNRTTYDKR LRPRYGEKPV  60
   61 DVGITIHVSS ISAVSEVDMD FTLDFYMRQT WQDPRLAFGS LDLGLSKEID SLTVGVDYLD 120
  121 RLWKPDTFFP NEKKSFFHLA TTHNSFLRIE GDGTVYTSQR LTVTATCPMD LKLFPMDSQH 180
  181 CKLEIESYAY STAEIEYKWC TSKEPNCSTA VKADANIELS SYKFTKICQK RTLASTSSGT 240
  241 YSRLRVSFIF DRDSGFYFLQ IFFPASLVVV LSWISFWINR DSAPSRTLIG TMTVLTETHL 300
  301 MTGTNRRLPP VAYVKAVDVF LGFCYLLVIL ALIEYACVAY SKKKNEDRRR REKKTEHKPA 360
  361 PPTPDILHDV RLAECTCNAA PTSIIAVIKQ SNRFCVSHSH IDIVSRAAFP LVFILFNTLF 420
  421 WLILLYKSKR LPYISEHEGD RCDAPDLH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..362] PSI-BLAST 68.30103 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [363..448] PSI-BLAST 27.30103 Acetylcholine receptor protein, delta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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