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View Structure Prediction Details

Protein: unc-49
Organism: Caenorhabditis elegans
Length: 448 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-49.

Description E-value Query
Range
Subject
Range
gi|39591873, gi|... - gi|39591873|emb|CAE71451.1| Hypothetical protein CBG18364 [Caenorhabditis briggsae], gi|187025367|em...
gi|157775779 - gi|157775779|ref|XP_001665955.1| hypothetical protein CBG18364 [Caenorhabditis briggsae AF16]
375.0 [0..1] [448..1]

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Predicted Domain #1
Region A:
Residues: [1-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPFTLIVL LSAHLCLHVV VTQDEDSHIN TQLLSSVLDR LTNRTTYDKR LRPRYGEKPV  60
   61 DVGITIHVSS ISAVSEVDMD FTLDFYMRQT WQDPRLAFGS LDLGLSKEID SLTVGVDYLD 120
  121 RLWKPDTFFP NEKKSFFHLA TTHNSFLRIE GDGTVYTSQR LTVTATCPMD LKLFPMDSQH 180
  181 CKLEIESYAY STAEIEYKWC TSKEPNCSTA VKADANIELS SYKFTKICQK RTLASTSSGT 240
  241 YSRLRVSFIF DRDSGFYFLQ IFFPASLVVV LSWISFWINR DSAPSRTLIG TMTVLTETHL 300
  301 MTGTNRRLPP VAYVKAVDVF LGFCYLLVIL ALIEYACVAY SKKKNEDRRR REKKTEHKPA 360
  361 PP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.30103
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [363-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPDILHDVRL AECTCNAAPT SIIAVIKQSN RFCVSHSHID IVSRAAFPLV FILFNTLFWL  60
   61 ILLYKSKRLP YISEHEGDRC DAPDLH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1oedC
Description: Acetylcholine receptor protein, delta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle