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Protein Overview: unc-49

General Information:
Name(s) found: unc-49 / CE28084 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006784 locus:unc-49 status:Confirmed UniProt:G5EFN4 protein_id:CAC42348.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 475 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    regulation of backward locomotion [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    gamma-aminobutyric acid signaling pathway [IMPLink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPFTLIVL LSAHLCLHVV VTQDEDSHIN TQLLSSVLDR LTNRTTYDKR LRPRYGEKPV  60
   61 DVGITIHVSS ISAVSEVDMD FTLDFYMRQT WQDPRLAFGS LDLGLSKEID SLTVGVDYLD 120
  121 RLWKPDTFFP NEKKSFFHLA TTHNSFLRIE GDGTVYTSQR LTVTATCPMD LKLFPMDSQH 180
  181 CKLEIESYGY ETKDIDYYWG KKRTDLEITA VKFDTFQLPQ FQPTLYFVNT TKAETSSGKY 240
  241 VRLALEVILV RNMGFYTMNI VIPSILIVTI SWVSFWLNRE ASPARVGLGV TTVLTMTTLI 300
  301 TTTNNSMPKV SYVKGLDVFL NFCFVMVFAS LLEYAIVSYM NKRLVLRREK RRKAAEQQQR 360
  361 NEMPMFNASP KAANNNNPLM EIPENCDCRT IPMMQHPRLV TDGAHTLWPA PFARPKKASK 420
  421 TCCQRWTPAK IDKLSRYGFP LSFSIFNIVY WLYMKYLSLN SSDKIQENDK WQQIH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..367] PSI-BLAST 63.69897 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [368..475] PSI-BLAST 27.0 Acetylcholine receptor protein, beta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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