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Protein Overview: unc-64

General Information:
Name(s) found: unc-64 / CE28035 [WormBase]
Description(s) found:
Found 24 descriptions.
SHOW ALL
  • WBGene00006798 locus:unc-64 Syntaxin-1A homolog status:Confirmed UniProt:O16000 protein_id:CAC42303.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    membrane [IEALink to PubMed article]
    neuronal cell body [IDALink to PubMed article]
    basolateral plasma membrane [IDALink to PubMed article]
    Biological Process: intracellular protein transport [IEALink to PubMed article]
    Molecular Function: protein transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKDRLSALK AAQSEDEQDD DMHMDTGNAQ YMEEFFEQVE EIRGSVDIIA NNVEEVKKKH  60
   61 SAILSNPVND QKTKEELDEL MAVIKRAANK VRGKLKLIEN AIDHDEQGAG NADLRIRKTQ 120
  121 HSTLSRRFVE VMTDYNKTQT DYRERCKGRI QRQLDIAGKQ VGDEDLEEMI ESGNPGVFTQ 180
  181 GIITDTQQAK QTLADIEARH NDIMKLESSI RELHDMFMDM AMLVESQGEM VDRIEYNVEH 240
  241 AKEFVDRAVA DTKKAVQYQS KARRKKICIL VTGVILITGL IIFILFYAKV L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..291] PSI-BLAST 39.522879 Syntaxin 1A N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphatidic acid binding
    		•  8.51970136264329 bayes_pls_golite062009
  • SNAP receptor activity
    		•  3.50393203740159 bayes_pls_golite062009
  • binding
    		•  2.76125772097759 bayes_pls_golite062009
  • SNARE binding
    		•  1.85060343142976 bayes_pls_golite062009
  • protein transporter activity
    		•  1.75171696421745 bayes_pls_golite062009
  • transporter activity
    		•  1.74189664015129 bayes_pls_golite062009
  • protein binding
    		•  1.61683263008775 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49085442233849 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.13101548288086 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.643064875848901 bayes_pls_golite062009
  • gated channel activity
    		•  0.621670335227137 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • extracellular-glutamate-gated ion channel activity
    		•  0.394485000881621 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.370484918396857 bayes_pls_golite062009
  • channel activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.0435980899803177 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0172309833091902 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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