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Protein Overview: itr-1

General Information:
Name(s) found: itr-1 / CE28017 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00002173 locus:itr-1 Inositol 1,4,5-trisphosphate receptor itr-1 status:Confirmed UniProt:Q9Y0A1 protein_id:CCD63765.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 2857 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDALink to PubMed article][IEALink to PubMed article]
    endoplasmic reticulum [TASLink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: regulation of pharyngeal pumping [IGILink to PubMed article][IMPLink to PubMed article]
    ion transport [IEALink to PubMed article]
    muscle contraction [IMPLink to PubMed article]
    calcium ion transport [IEALink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    defecation [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    rhythmic behavior [IMPLink to PubMed article]
    elevation of cytosolic calcium ion concentration [IDALink to PubMed article]
    Molecular Function: inositol-1,4,5-trisphosphate receptor activity [ISSLink to PubMed article]
    ion channel activity [IEALink to PubMed article]
    calcium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYDYRRRVL ERNIGMALPS RKLTIANSID HGNNGNLHIG DIISLYTESS SNQEQRGFLS  60
   61 TLGLVDDRCI VELKDGRPES PPKKFRDCLF KVCPVNRYAA QKHLWTEQKR FQTGDSMFDD 120
  121 DLMNKLKVAA DKEREENESE FQKTLGNVIQ YGSMVQLLHV KSNKYITVQK NSPAKRERNA 180
  181 MKVYLDRAGN EGSWFIIEPA YKHYAIGDNV SAGNKISLIP NSVSTTQAGH VKSQLHLSSF 240
  241 NLLDHQSAAE VNCLNEPTEW QVFMFLLFDE NQQNSVKSGD VVRLFHADQQ TFLTLDTIPK 300
  301 QNPPTDVVFL RMTNRPSAAD ATSSRALWEV QVVQTNAYRG GTAKWNKAYR FKHLATDMYL 360
  361 SAEPSQVQVK PAMNGRPPLL SALSQKSRPM LERTNNPMAM YSDGPNGVTN ESTDTTQQNI 420
  421 PSVWVLGPTK SEFPEEDANL LFQLDPSTFM KSNKEVPRRS YVRLLHQSSD KWVHATNATE 480
  481 KQNLHYSSKN EKGWVKVICE KNRVDKETFA LLPVNPDEVR DLDFANDACK ALRNFIKLIK 540
  541 IGQVISKESI NSTTQLLIDC ILFVTNSSDH LADPLKISDF SPSRDRQKLL REQEVLNQVF 600
  601 LLLKAPFLPR QGTTELGPLL SSPSELSDSR NEIFKTMFQL CYCLLKYSQV SYRKNQEFLA 660
  661 EKFGEIQEQI GFDLMAEDTM TAVLHNNPKL LEKYVKTPHV ERFVELVRNN RQGKFLDYLA 720
  721 DLCVCRGEAN KKIQELICTS VLSSKHRDIF MDTKIIDGEI EVGWAPNFRK LVDIAEGAKS 780
  781 NSDDAEHLDY YRHQLDLLSQ MCQEQQYLAI DPPPERRLMN ISQQLPAELV LQCMSDNRLP 840
  841 YDLRGSFTRL MLHLHVVRGS PMSAIRHARL WWSIPENVNV STYESVSVEA YSDGSRMRIG 900
  901 EGIAHKVLAT VETYLMGLRN QSMEERQSVN SSKLTYEIVN LAKALAQFNF YSFNDLLQLT 960
  961 QNLLAIINEG PATEQVPSHR AMVNAIRNMS KSMMRGGNKE NSKDLAKTPS VTAEEAGRTK1020
 1021 EGRALNVKTK LIVAEILQFV MDVRRDYRIT MALSWFKNVF PCDEDGSLMH SASINERMAS1080
 1081 ELYDAIYRSS GHELHLDGRD GQLLLAILLQ MTMSDYPPLT SIALKVFFRH FTQYQELLED1140
 1141 LKQVQLLVSN NDVENYRQID RDLFILKNLT EKSELWVHGD RHHSIDTKEV DEKERTTEHD1200
 1201 LLDHDLKSPR AFDSGDSMEA LMAVLNEHYP SIRNECLQLL NRLLIKDDRN DAAVALQELS1260
 1261 DKAPLIAYPL IRQMLVRLTG MCYRKGDPKP DTMNQQLLKN MRVYEVVLEF ISVPHDKKHD1320
 1321 HDMMKLITLS HEFLRSFCKT NKENQSRLYK FISYEKDAKE GMLRVETIEE VGTLVAIFRN1380
 1381 NRELASNVPE ELIAHIVGLI EHNSRNPIFL ELLQALVCVY DKEIESGQEK VANEICAASD1440
 1441 EVRQLYVDNA SFEELEAMMK DEKESKGRSS DSRRKLKYHI ELVRLLAMCT RGKNGNTELK1500
 1501 CASQIPMDHI VRVVTAKQCL VEVKTVYLQL LLHCYIDTDA EMKDAYKTEY VDHILNNLLE1560
 1561 DIRSLRVEKL TGAETATLEH YICHTVTEVL IKFFEAPYSA LQQAKVDVHH HKKTFSEVLL1620
 1621 ELTYLEKGKL RGSKSSRNWY RVAECIKRLT KWAEEHNITL PATLAGPQMS GQTSVRQKWQ1680
 1681 QAASSAKWIG IGKRLNRQNT LNPGHRLYGT SNSMTEHTSA NVVTCYHMMI GEFKFYLHPL1740
 1741 HAAEGSVLVE VLHTPELLFP EGSALRDQCA RGGVVAKLIQ HCKTLMQNKQ DNLCARVLQT1800
 1801 LCKMCDCTKQ QLTHQGHRVY NSSVEKGQQL RQLLLQRYFG HHNNHHPPLD RQQSKIGEVI1860
 1861 EAVKEKKEET WSQERDLYAI QCKLNDAGAS DLVTDIIIME PSREIFLKAI HLARALLHEG1920
 1921 NDKVQHSFYM RMKQKDIHEP FFKAILTRIQ TAQNRLKSDM MSCSDSKPKV SSTVLTPLID1980
 1981 AGDTGFNGAL FEVPQQVRHP SISEMSQLSN DLTHSIPDLA PYQDEEKSTD ALPPEVALVE2040
 2041 PILRVLQLLC ENHNSLLQNF LRKQSDRTNH NLVSETLSFL DTVCGSTKGS LGVFGEIGEH2100
 2101 NFSLITQTLA TLTEFCQGPC HENQNTMAMQ ENGLNIIISL VLNEIKPLAD DHMELALEIK2160
 2161 SQASKLLLAI MESRHDGENA NRVLRNMANM SGGPKQLVHA IKQAYEMTNS NHHMLKSISR2220
 2221 DLFRQAEDDL KKKSGPQITV NTVTLPEINV DASGIVSIHT EKNISSSLDD KFNDDDIPSV2280
 2281 DPREVGHNIY ILAHQLAIHD GELEIWLDGS DEKKDDLTRE ALNYYKERTA QIEIVRRDRT2340
 2341 LERVVFPIND ICSYLTKDTK DYVYNNTERD NQGSKVTEFF DEWETMYHEM IWQRKLQDRK2400
 2401 WLSWCAFRLP LWTRLSFHFA FIVNALVARY YPLPEHSNSS ISLGNLYSWF AVFSSFLLAH2460
 2461 YLRHDKIYLH KTSLLILASL CFLLLSSIGV TLTLYIFGIL QLVNKIVHVV AFVSNKGLED2520
 2521 RPIAEILACR NLHYLLVYLF ICILGLLVHP MIYCILLFDI IFTEETLQNV IASVTRNYQS2580
 2581 IVWTGLLALI LLYFFSILGF LYFRHDFYLE VDPVENDSSA TISSGIPSET CPSEGCPGLQ2640
 2641 PSEKDDNDDE KKVKSCETLW MCILQTGYQG LRNGGGIGDV LRNPAPWEDM FIWRVAYDMT2700
 2701 FFVVLIVIVL NLIFGVIIDT FGDLRAEKNE KEQILKNNCF ICGLDRSRFD NRSVTFETHR2760
 2761 ETEHNIWHYL YYIVMLQIKD ETEFTGPESY VAQCVKDRNL DWFPRMQALS LQDSELDTDQ2820
 2821 SEVKQMKDQL LQMMTLMREI ISQNEESRAF MEQFQPR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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