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Protein Overview: ins-1

General Information:
Name(s) found: ins-1 / CE27955 [WormBase]
Description(s) found:
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  • WBGene00002084 locus:ins-1 status:Confirmed UniProt:G5EFY8 protein_id:CAC42282.1 [WormBase]
  • pir||JE0286 insulin-like protein 1 [imported] - Caenorhabditis elegans [NCBI NR]
  • gi|3220259|gb|AAC33275.1| insulin-like peptide [Caenorhabditis elegans] [NCBI NR]
  • gi|17539802|ref|NP_501926.1| INSulin related family member (ins-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530429|emb|CAC42282.1| C. elegans protein F13B12.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27955 WBGene00002084 locus:ins-1 status:Confirmed TR:O76469 protein_id:CAC42282.1 [wormpep150.fasta]
  • 27955 WBGene00002084 locus:ins-1 status:Confirmed TR:O76469 protein_id:CAC42282.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • INSulin related (12.4 kD) (ins-1) [Caenorhabditis elegans]gi|14530429|emb|CAC42282.1| Hypothetical protein F13B12.5 [Caenorhabditis elegans]gi|7522609|pir||JE0286 insulin-like protein 1 [imported] - Caenorhabditis elegansgi|3220259|gb|AAC33275.1| insul [nrdb_11152004_Chlamydomonas]
  • locus:ins-1 status:Confirmed TR:O76469 protein_id:CAC42282.1 [wormpep115.fasta.reversed]
  • CE27955 locus:ins-1 status:Confirmed TR:O76469 protein_id:CAC42282.1 [wormpep80.hongbin]
  • CE27955 WBGene00002084 locus:ins-1 status:Confirmed UniProt:O76469_CAEEL protein_id:CAC42282.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27955 WBGene00002084 locus:ins-1 status:Confirmed UniProt:O76469_CAEEL protein_id:CAC42282.1| [wormORF-contam.fasta]
  • insulin-like peptide [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F13B12.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • INSulin related family member (ins-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE27955 WBGene00002084 locus:ins-1 status:Confirmed UniProt:O76469 protein_id:CAC42282.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE27955 WBGene00002084 locus:ins-1 status:Confirmed UniProt:G5EFY8 protein_id:CAC42282.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • INSulin related OS=Caenorhabditis elegans GN=ins-1 PE=2 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 109 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article]
    Biological Process: regulation of chemotaxis [IMP]
    negative regulation of insulin receptor signaling pathway [IGI][IMP]
    learning or memory [IMP]
    Molecular Function: hormone activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYWFRQVYRP SFFFGFLAIL LLSSPTPSDA SIRLCGSRLT TTLLAVCRNQ LCTGLTAFKR  60
   61 SADQSYAPTT RDLFHIHHQQ KRGGIATECC EKRCSFAYLK TFCCNQDDN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] FFAS03 4.28 Insulin-like growth factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • insulin receptor binding
    		•  2.7278725657614 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  2.52789753864303 bayes_pls_golite062009
  • receptor binding
    		•  1.96314913282044 bayes_pls_golite062009
  • binding
    		•  1.53606661868923 bayes_pls_golite062009
  • protein binding
    		•  1.03308976416246 bayes_pls_golite062009
  • growth factor activity
    		•  0.882616311405838 bayes_pls_golite062009
  • protein complex binding
    		•  0.391427446215436 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle