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Protein Overview: cas-2

General Information:
Name(s) found: cas-2 / CE27714 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00015975 locus:cas-2 Adenylyl cyclase-associated protein status:Partially_confirmed UniProt:O02096 protein_id:CCD65141.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 457 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of adenylate cyclase activity [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    Molecular Function: adenylate cyclase binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPSVVSRLE NVANRTENIL LKYDSNKKET PVDATPQIIN LYDDAICENL VSFYDLSAKI  60
   61 GGDLNRLGCM TRSLFFTHRY FLWIACGRKK ADNDEFATLV NDLSKEIVAF SDFKEKNRKS 120
  121 EFYNHICGLE AAVGGFGWVA EPKTPAPFIK DAIDTSVFYL NRILMEHKGK NDFHSEWAKS 180
  181 IKELMLSLHE YVRQHHTTGL VWNSDPGATP MCNRKSGGAP TPPPPPPPPI SLIAPSKPSG 240
  241 VGALLESLNT GLSATSRLKK VTPEMQTHKN PVLREVNGQM NRKTEERKVS ENKKPEKIHE 300
  301 SSIFWDGKIW KVDHQVGNKN AVVEVTDKKE SIYIYKCNDS IIKIKGKANA ITLDGCRKTS 360
  361 VVFDGLVAQC EIINCQSIQI QTLGELPTVS IQKTDGCHIY LSRDALNAQI VASKSSEMNI 420
  421 SAMLEDGDDE YTEMALPEQF MTKIVGKKLV TVASEIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] PSI-BLAST 64.221849 The crystal structure of the N-terminal domain of CAP indicates variable oligomerisation
    2 View Details [236..298] MSA 1.052987 View MSA. No confident structure predictions are available.
    3 View Details [299..457] PSI-BLAST 73.09691 C-terminal domain of adenylylcyclase associated protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  5.81884714997094 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.39652693178112 bayes_pls_golite062009
  • adenylate cyclase binding
    		•  1.89694035952868 bayes_pls_golite062009
  • binding
    		•  1.8340549733034 bayes_pls_golite062009
  • enzyme binding
    		•  1.53072876683435 bayes_pls_golite062009
  • protein binding
    		•  0.871734119777931 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • actin binding
    		•  4.94933252861141 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.21664682046338 bayes_pls_golite062009
  • actin monomer binding
    		•  2.04365563273836 bayes_pls_golite062009
  • binding
    		•  1.57578562719958 bayes_pls_golite062009
  • adenylate cyclase binding
    		•  0.947630973686921 bayes_pls_golite062009
  • enzyme binding
    		•  0.705135358375 bayes_pls_golite062009
  • protein binding
    		•  0.651719649953198 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle