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Protein Overview: npp-8

General Information:
Name(s) found: npp-8 / CE27625 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003794 locus:npp-8 status:Confirmed UniProt:Q95Y13 protein_id:CCD66718.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 411 amino acids

    Gene Ontology:
    Cellular Component: nuclear pore [IEALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    nucleocytoplasmic transport [IEALink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    nucleus organization [IMPLink to PubMed article]
    Molecular Function: structural constituent of nuclear pore [IEALink to PubMed article]
    nucleocytoplasmic transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSFMELGS ADSAEAAANK VAHHVEQMME TSDFFDRLTQ HGTTPVSGLG EKFYVKGAPE  60
   61 FVSTRRIPIP GELQMQMSNI HSEFSMGFFT QISRVWVVID NNLYMWNYET NDDLAFFDSS 120
  121 DAAILKVSLV NIKPGVFEPE IQYGLVVGTI SDICLYPVFD FVENGASSIS IDSKRCFKIA 180
  181 LDGATVNDIS YTSNGRVFYT ADDQLFEFVY EKQNGWFGST NHKCRGVNQT ASILGTLISL 240
  241 PFFGSSKEPL DQITIDKSRN IMYLLGRAGT VSVWDLGADG AACAKFLSVP ISKIAHEAHI 300
  301 LTQFGHDETS FHSITSIKAL EASQSAALNL VATTAKGVRL YFSVSTGPQS TMAMFNNSGT 360
  361 PNERNRPQTS VRPQCLRVAH VRFAPGVTPA SIYGDGPNGV SVVYADECTR L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..348] FFAS03 1.23 The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
    2 View Details [349..411] MSA 1.029991 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle