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View Structure Prediction Details

Protein: npp-8
Organism: Caenorhabditis elegans
Length: 411 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for npp-8.

Description E-value Query
Range
Subject
Range
gi|28277555, gi|... - gi|41055863|ref|NP_956450.1| nucleoporin 155 [Danio rerio], gi|28277555|gb|AAH45339.1| Nucleoporin 1...
517.0 [0..12] [411..16]

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Predicted Domain #1
Region A:
Residues: [1-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSFMELGS ADSAEAAANK VAHHVEQMME TSDFFDRLTQ HGTTPVSGLG EKFYVKGAPE  60
   61 FVSTRRIPIP GELQMQMSNI HSEFSMGFFT QISRVWVVID NNLYMWNYET NDDLAFFDSS 120
  121 DAAILKVSLV NIKPGVFEPE IQYGLVVGTI SDICLYPVFD FVENGASSIS IDSKRCFKIA 180
  181 LDGATVNDIS YTSNGRVFYT ADDQLFEFVY EKQNGWFGST NHKCRGVNQT ASILGTLISL 240
  241 PFFGSSKEPL DQITIDKSRN IMYLLGRAGT VSVWDLGADG AACAKFLSVP ISKIAHEAHI 300
  301 LTQFGHDETS FHSITSIKAL EASQSAALNL VATTAKGVRL YFSVSTGP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.23
Match: 1xksA
Description: The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [349-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSTMAMFNNS GTPNERNRPQ TSVRPQCLRV AHVRFAPGVT PASIYGDGPN GVSVVYADEC  60
   61 TRL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle