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Protein Overview: bre-4

General Information:
Name(s) found: bre-4 / CE26412 [WormBase]
Description(s) found:
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  • WBGene00000269 locus:bre-4 status:Confirmed UniProt:Q9GUM2 protein_id:CCD73531.1 [WormBase]
  • gi|75022270|sp|Q9GUM2.1|BRE4_CAEEL RecName: Full=Beta-1,4-N-acetylgalactosaminyltransferase bre-4; AltName: Full=Beta-4-GalNAcT; AltName: Full=Bacillus thuringiensis toxin-resistant protein 4; Short=Bt toxin-resistant protein 4 [NCBI NR]
  • gi|42601222|gb|AAS21308.1| BRE-4 [Caenorhabditis elegans] [NCBI NR]
  • gi|22415755|gb|AAM95168.1| UDPGalNAc:GlcNAc{beta}-R {beta}1,4-N-acetylgalactosaminyltransferase [Caenorhabditis elegans] [NCBI NR]
  • gi|17510623|ref|NP_490872.1| BT (Bacillus thuringiensis) toxin REsistant family member (bre-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|10800389|gb|AAG23384.1| Bt (bacillus thuringiensis) toxin resistant protein 4 [Caenorhabditis elegans] [NCBI NR]
  • Beta-1,4-N-acetylgalactosaminyltransferase bre-4 OS=Caenorhabditis elegans GN=bre-4 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE26412 WBGene00000269 locus:bre-4 status:Confirmed TR:Q9GUM2 protein_id:AAG23384.1 [wormpep150.fasta]
  • 26412 WBGene00000269 locus:bre-4 status:Confirmed TR:Q9GUM2 protein_id:AAG23384.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • {beta}4GalNAcT: UDPGalNAc:GlcNAc{beta}-R {beta}1,4-N-acetylgalactosaminyltransferase (43.9 kD) (1C94) [Caenorhabditis elegans]gi|10800389|gb|AAG23384.1| Bt (bacillus thuringiensis) toxin resistant protein 4 [Caenorhabditis elegans]gi|22415755|gb|AAM9516 [nrdb_11152004_Chlamydomonas]
  • status:Confirmed TR:Q9GUM2 protein_id:AAG23384.1 [wormpep115.fasta.reversed]
  • CE26412 status:Predicted TR:Q9GUM2 protein_id:AAG23384.1 [wormpep80.hongbin]
  • CE26412 WBGene00000269 locus:bre-4 status:Confirmed UniProt:Q9GUM2 protein_id:AAG23384.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE26412 WBGene00000269 locus:bre-4 status:Confirmed UniProt:Q9GUM2 protein_id:AAG23384.1| [wormORF-contam.fasta]
  • UDPGalNAc:GlcNAc{beta}-R {beta}1,4-N-acetylgalactosaminyltransferase [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • BT (Bacillus thuringiensis) toxin REsistant family member (bre-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Bt (bacillus thuringiensis) toxin resistant protein 4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • BRE-4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE26412 WBGene00000269 locus:bre-4 status:Confirmed UniProt:Q9GUM2 protein_id:CCD73531.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE26412 WBGene00000269 locus:bre-4 status:Confirmed UniProt:Q9GUM2 protein_id:CCD73531.1 Beta-1,4-N-acetylgalactosaminyltransferase bre-4 [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    response to toxin [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of Notch signaling pathway [IGILink to PubMed article]
    Molecular Function: transferase activity, transferring glycosyl groups [IEALink to PubMed article]
    xylose isomerase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRHLAVAR LKSLLVLCAV LLLVHAMIYK IPSLYENLTI GSSTLIADVD AMEAVLGNTA  60
   61 STSDDLLDTW NSTFSPISEV NQTSFMEDIR PILFPDNQTL QFCNQTPPHL VGPIRVFLDE 120
  121 PDFKTLEKIY PDTHAGGHGM PKDCVARHRV AIIVPYRDRE AHLRIMLHNL HSLLAKQQLD 180
  181 YAIFIVEQVA NQTFNRGKLM NVGYDVASRL YPWQCFIFHD VDLLPEDDRN LYTCPIQPRH 240
  241 MSVAIDKFNY KLPYSAIFGG ISALTKDHLK KINGFSNDFW GWGGEDDDLA TRTSMAGLKV 300
  301 SRYPTQIARY KMIKHSTEAT NPVNKCRYKI MGQTKRRWTR DGLSNLKYKL VNLELKPLYT 360
  361 RAVVDLLEKD CRRELRRDFP TCF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] MSA 1.039994 View MSA. No confident structure predictions are available.
    2 View Details [85..383] PSI-BLAST 105.0 beta 1,4 galactosyltransferase (b4GalT1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  8.87768693404638 bayes_pls_golite062009
  • lactose synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • N-acetyllactosamine synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  6.50620584399191 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  6.18010634203776 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.57855076532185 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.57071306027628 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  3.80392076707564 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  3.57513377728523 bayes_pls_golite062009
  • transferase activity
    		•  2.62166586999833 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  2.58196286090865 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  2.49617255507474 bayes_pls_golite062009
  • heparan sulfate N-acetylglucosaminyltransferase activity
    		•  2.42139682088952 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.01768771829228 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  1.6603302881547 bayes_pls_golite062009
  • beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
    		•  1.33105118629174 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.31793036737589 bayes_pls_golite062009
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
    		•  1.11758321292207 bayes_pls_golite062009
  • protein binding
    		•  0.967722609820275 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.734643988700831 bayes_pls_golite062009
  • binding
    		•  0.667238976803188 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.218759888732981 bayes_pls_golite062009
  • glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  0.119213830545019 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009
  • mannose-1-phosphate guanylyltransferase activity
    		•  0.040911758618571 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0278258721775009 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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