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Protein Overview: obr-1

General Information:
Name(s) found: obr-1 / CE26105 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00012930 locus:obr-1 Oxysterol-binding protein status:Partially_confirmed UniProt:Q9U2C7 protein_id:CAB57894.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 766 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    steroid metabolic process [IEALink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLSEFLRK RRARQRRLQA VPSNNKKKSN NNNIMSSTSS GKSRRAASLS SINNFEHLAS  60
   61 VEKAGWLNKW TNYLKGYRQR WFVLDSNATL SYYRNPSEVG HTCRGSINLQ EARVHTDKTT 120
  121 SCIVISGQSQ TFHVKPQNEM DRQQWTNSLE YMRHKAITRA ESEEDEDAQM AKTDSNRSDA 180
  181 LILANRQMSG KLCDLRTAAN MMNKQGDELM RALNGTVETD KNSLAERADL LKMTTSAVLQ 240
  241 AAEEFVELSE QSAKRLNKIV AVEQKEKALL QEQLEALAKQ HSSLERAASK CARGAAPVSV 300
  301 YSDQEDDEFH DAEEDLAMPC SNSNGPPATA GVHLTPTKRH IGAGDPSSST CSDSGAVVVV 360
  361 GAHKGGRQRR TTVPERPNLP INLWSIMKNC IGKELSKIPM PVNFSEPISV LQRVTEDLEY 420
  421 ANLLETGAKL STLEQMCYVA AYAASNYSTT CHRTNKPFNP LLGETFEFDR MDDLGWRSVT 480
  481 EQVSHHPPAA AHHAEGNGWT MYQDFTMTSR FRGKYLSVIP IGFTHVVFPA TKSHFSYRKI 540
  541 TTTVHNIIVG KLWIDNHGDM EITNHETNEK CLLKFVPYSY FSREQPRKVY GIVRDAEGIP 600
  601 KYVVQGTWDK SIDMLKVSSW NGNHEKPKLE VDETSLKRIW TANPLPKNAE KMHNFTKLAI 660
  661 ELNEPEEGVA PTDSRLRPDQ RLMENGEWDE ANRKKLEIEE KQRVVRRRRE AEKELAMKKG 720
  721 DKYEEYEPTW FVRVQDESNG ALIHQFKGGY WEAKEQQNWE KCPDIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 12.522879 Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
    2 View Details [160..364] FFAS03 1.25 Fibrinogen C-terminal domains; Fibrinogen gamma chain
    3 View Details [365..766] PSI-BLAST 59.0 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.42470476396787 bayes_pls_golite062009
  • protein binding
    		•  2.1446140694885 bayes_pls_golite062009
  • receptor binding
    		•  0.3173431866346 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle