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View Structure Prediction Details

Protein: obr-1
Organism: Caenorhabditis elegans
Length: 766 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for obr-1.

Description E-value Query
Range
Subject
Range
gi|157821825, gi... - gi|157821825|ref|NP_001100702.1| oxysterol binding protein 2 [Rattus norvegicus], gi|149047523|gb|ED...
575.0 [0..12] [766..118]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLSEFLRK RRARQRRLQA VPSNNKKKSN NNNIMSSTSS GKSRRAASLS SINNFEHLAS  60
   61 VEKAGWLNKW TNYLKGYRQR WFVLDSNATL SYYRNPSEVG HTCRGSINLQ EARVHTDKTT 120
  121 SCIVISGQSQ TFHVKPQNEM DRQQWTNSLE YMRHKAITR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1u5eA
Description: Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42470476396787 bayes_pls_golite062009
protein binding 2.1446140694885 bayes_pls_golite062009
receptor binding 0.3173431866346 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [160-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AESEEDEDAQ MAKTDSNRSD ALILANRQMS GKLCDLRTAA NMMNKQGDEL MRALNGTVET  60
   61 DKNSLAERAD LLKMTTSAVL QAAEEFVELS EQSAKRLNKI VAVEQKEKAL LQEQLEALAK 120
  121 QHSSLERAAS KCARGAAPVS VYSDQEDDEF HDAEEDLAMP CSNSNGPPAT AGVHLTPTKR 180
  181 HIGAGDPSSS TCSDSGAVVV VGAHK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.25
Match: 1m1jC
Description: Fibrinogen C-terminal domains; Fibrinogen gamma chain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [365-766]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGRQRRTTVP ERPNLPINLW SIMKNCIGKE LSKIPMPVNF SEPISVLQRV TEDLEYANLL  60
   61 ETGAKLSTLE QMCYVAAYAA SNYSTTCHRT NKPFNPLLGE TFEFDRMDDL GWRSVTEQVS 120
  121 HHPPAAAHHA EGNGWTMYQD FTMTSRFRGK YLSVIPIGFT HVVFPATKSH FSYRKITTTV 180
  181 HNIIVGKLWI DNHGDMEITN HETNEKCLLK FVPYSYFSRE QPRKVYGIVR DAEGIPKYVV 240
  241 QGTWDKSIDM LKVSSWNGNH EKPKLEVDET SLKRIWTANP LPKNAEKMHN FTKLAIELNE 300
  301 PEEGVAPTDS RLRPDQRLME NGEWDEANRK KLEIEEKQRV VRRRREAEKE LAMKKGDKYE 360
  361 EYEPTWFVRV QDESNGALIH QFKGGYWEAK EQQNWEKCPD IF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle