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Protein Overview: sma-3

General Information:
Name(s) found: sma-3 / CE25974 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00004857 locus:sma-3 Dwarfin sma-3 status:Confirmed UniProt:P45896 protein_id:CCD70180.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: positive regulation of cell size [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of organ growth [IMPLink to PubMed article]
    tail tip morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGLLHMHGP AVKKLLGWKI GEDEEKWCEK AVEALVKKLK KKNNGCGTLE DLECVLANPC  60
   61 TNSRCITIAK SLDGRLQVSH KKGLPHVIYC RVWRWPDISS PHELRSIDTC SYPYESSSKT 120
  121 MYICINPYHY QRLSRPQGLN SSMPSPQPIS SPNTIWQSSG SSTASCASSP SPSVFSEDGG 180
  181 EVQVHQRPPP FRHPKSWAQI TYFELNSRVG EVFKLVNLSI TVDGYTNPSN SNTRICLGQL 240
  241 TNVNRNGTIE NTRMHIGKGI QLDNKEDQMH IMITNNSDMP VFVQSKNTNL MMNMPLVKVC 300
  301 RIPPHSQLCV FEFNLFFQML EQSCNDSDGL NELSKHCFIR ISFVKGWGED YPRQDVTSTP 360
  361 CWLELRLNVP LAYIDQKMKQ TPRTNLMEPN SMT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 55.39794 Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution
    2 View Details [148..393] PSI-BLAST 91.522879 Smad1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.11808492882744 bayes_pls_golite062009
  • protein binding
    		•  1.57677875769005 bayes_pls_golite062009
  • transforming growth factor beta receptor, cytoplasmic mediator activity
    		•  0.20688121694899 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase signaling protein activity
    		•  0.17825540288715 bayes_pls_golite062009
  • signal transducer activity
    		•  0.15088578328411 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.15088578328411 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle