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Protein Overview: cas-1

General Information:
Name(s) found: cas-1 / CE25885 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000294 locus:cas-1 Adenylyl cyclase-associated protein status:Confirmed UniProt:H2L023 protein_id:CCD71056.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 495 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of adenylate cyclase activity [IEALink to PubMed article]
    Molecular Function: adenylate cyclase binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTQEDFLKR LESVTSRLEA IAGQKPALAP KPTNLGGPSA SAAASAGDSG EVPAHVRAYD  60
   61 DAIEEPLANW SKLTDQLGGD LAAVKPKVLA MFASMRNYLW SAAGKSEPSA EEAQKMLTPV 120
  121 INLLGEINNF KDTKRKTPHW NHLNSVAEAL PALGWVTVKK TPAPYVKEFI EAAQFYINPI 180
  181 LREFKETDPR HVEWTKAWKA VFEEMQKFVR QVHTTGLVWN SAPGAAPDAS ASAPSAAAPS 240
  241 APKAPAGPGG PPPPPPPPPA DFFANIAPPP VDADKASRDA LFASLNQGEG VTSRLKKVTA 300
  301 DMQTHKNPNL RGTAVVPAAG ASQGGSSPAK PAAPVRKPPH KELENGKQWI VEYFVNDPNI 360
  361 VLDVADKKQT VYIYRCENSV IKVNGKANSI TLDGCKKTSV VFDALVAQCE TVNCQSVQIQ 420
  421 TLGELPTLSI QKTDGCQVYL SKVAQGCEIV TSKSSEMNIS VQTNDDGDYS EFPVPEQFKT 480
  481 TFVNGKLVTV VSDIC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..216] PSI-BLAST 62.522879 The crystal structure of the N-terminal domain of CAP indicates variable oligomerisation
    2 View Details [217..338] MSA 2.111996 View MSA. No confident structure predictions are available.
    3 View Details [339..495] PSI-BLAST 74.221849 C-terminal domain of adenylylcyclase associated protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  1.59850944021401 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.08859857656487 bayes_pls_golite062009
  • binding
    		•  0.923764328759134 bayes_pls_golite062009
  • enzyme binding
    		•  0.47575292047999 bayes_pls_golite062009
  • protein binding
    		•  0.153255883232138 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  0.90871846524713 bayes_pls_golite062009
  • actin binding
    		•  0.72899481885448 bayes_pls_golite062009
  • binding
    		•  0.665494982655313 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle