Protein Overview: dat-1

General Information:
Name(s) found:	dat-1 / CE25124 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000934 locus:dat-1 Sodium-dependent dopamine transporter status:Confirmed UniProt:Q03614 protein_id:CAA79575.2 [WormBase] gi\|6434319\|emb\|CAA79575.2\| C. elegans protein T23G5.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|6434301\|emb\|CAA79564.2\| C. elegans protein T23G5.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|3982785\|gb\|AAC83661.1\| sodium- and chloride-dependent antidepressant- and cocaine-sensitive dopamine transporter [Caenorhabditis elegans] [NCBI NR] gi\|17555248\|ref\|NP_499043.1\| DopAmine transporter family member (dat-1) [Caenorhabditis elegans] [NCBI NR] gi\|14917020\|sp\|Q03614.3\|NTDO_CAEEL RecName: Full=Sodium-dependent dopamine transporter; Short=DA transporter; Short=DAT [NCBI NR] pir\|\|T43330 catecholamine transport protein - Caenorhabditis elegans [NCBI NR] Sodium-dependent dopamine transporter OS=Caenorhabditis elegans GN=dat-1 PE=2 SV=3 [Swiss-Prot] [wormpep67.fasta] CE25124 WBGene00000934 locus:dat-1 sodium:neurotransmitter symporter status:Confirmed SW:Q03614 protein_id:CAA79575.2 [wormpep150.fasta] 25124 WBGene00000934 locus:dat-1 sodium:neurotransmitter symporter status:Confirmed SW:Q03614 protein_id:CAA79575.2 [wormpep130-phg-ecoli-orf-rand.fasta] dopamine transporter, antidepressant and cocaine-sensitive (69.3 kD) (dat-1) [Caenorhabditis elegans]gi\|6434319\|emb\|CAA79575.2\| Hypothetical protein T23G5.5 [Caenorhabditis elegans]gi\|6434301\|emb\|CAA79564.2\| Hypothetical protein T23G5.5 [Caenorhabditis [nrdb_11152004_Chlamydomonas] locus:dat-1 sodium:neurotransmitter symporter status:Confirmed SW:Q03614 protein_id:CAA79575.2 [wormpep115.fasta.reversed] CE25124 locus:dat-1 sodium:neurotransmitter symporter status:Confirmed SW:Q03614 protein_id:CAA79575.2 [wormpep80.hongbin] CE25124 WBGene00000934 locus:dat-1 sodium:neurotransmitter symporter status:Confirmed UniProt:Q03614 protein_id:CAA79575.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE25124 WBGene00000934 locus:dat-1 sodium:neurotransmitter symporter status:Confirmed UniProt:Q03614 protein_id:CAA79575.2\| [wormORF-contam.fasta] Sodium-dependent dopamine transporter (DA transporter) (DAT) [nr-271106-contam.fasta] Hypothetical protein T23G5.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] DopAmine transporter family member (dat-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] sodium- and chloride-dependent antidepressant- and cocaine-sensitive dopamine transporter [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE25124 WBGene00000934 locus:dat-1 status:Confirmed UniProt:Q03614 protein_id:CAA79575.2 Sodium-dependent dopamine transporter [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	615 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] membrane [IEA]
Biological Process:	neurotransmitter transport [IEA] dopamine uptake [IDA ] amine transport [IMP] chloride transport [IDA]
Molecular Function:	neurotransmitter:sodium symporter activity [IEA] dopamine:sodium symporter activity [IDA ] amine transmembrane transporter activity [IMP] chloride channel activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLVPTDDPD EKIGRTSNGM QNATLPIDGP VNTEPKDPAR EQWSGKLDFL LSVVGFAVDL  60
   61 GNIWRFPYLC FKNGGGVFLI PYSIMVLLTG VPLFYMELCL GQYYRKGAIT TWGRICPLFK 120
  121 GIGYCVILTA FYVDFFYNVI LAWGLHYLYT SFSFNLPWAS CNNSYNSPAC YEPHWSEDGT 180
  181 AMCRSANQSV SAEKISAAEE YFYKGFLGLH EANAPNSHVI RSVTDLGNVR WDIALSLFVV 240
  241 YLICYFSMWK GIHTSGKVVW FTALFPYVVL GILFIRGVTL PGWQNGIEYY LRPNFEMLKR 300
  301 PSVWQDAATQ VFFSLGPGFG VLMAYSSYND FHNNVYVDAL FTSFINCATS FLSGFVIFSV 360
  361 LGYMSCKSGK PIEAVAQEGP GLVFVVYPEA LSTMPYAPFW SVLFFLMLMT LGLDSSFGGS 420
  421 EAIITGLSDE FPILKKNREV FVGCLFAFYM VIGIAMCTEG GILIMEWLII YGTTWGLLIA 480
  481 VFCEAMVIAY IYGLRQFVHD VKEMMGFRPG NYWKFCWSCA APFILLSMIT SNFINYQALT 540
  541 YQDYTYPTAA NVIGIIFALS GASFIPLVGI YKFVNARGNT ISEKWQRVTM PYRKRPNQTE 600
  601 YIPIPTTQPH SDIML

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..615]	PSI-BLAST	59.045757	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters

Protein Overview: dat-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: