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Protein Overview: dat-1

General Information:
Name(s) found: dat-1 / CE25124 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00000934 locus:dat-1 Sodium-dependent dopamine transporter status:Confirmed UniProt:Q03614 protein_id:CAA79575.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    Biological Process: neurotransmitter transport [IEALink to PubMed article]
    dopamine uptake [IDALink to PubMed articleLink to PubMed article]
    amine transport [IMPLink to PubMed article]
    chloride transport [IDALink to PubMed article]
    Molecular Function: neurotransmitter:sodium symporter activity [IEALink to PubMed article]
    dopamine:sodium symporter activity [IDALink to PubMed articleLink to PubMed article]
    amine transmembrane transporter activity [IMPLink to PubMed article]
    chloride channel activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLVPTDDPD EKIGRTSNGM QNATLPIDGP VNTEPKDPAR EQWSGKLDFL LSVVGFAVDL  60
   61 GNIWRFPYLC FKNGGGVFLI PYSIMVLLTG VPLFYMELCL GQYYRKGAIT TWGRICPLFK 120
  121 GIGYCVILTA FYVDFFYNVI LAWGLHYLYT SFSFNLPWAS CNNSYNSPAC YEPHWSEDGT 180
  181 AMCRSANQSV SAEKISAAEE YFYKGFLGLH EANAPNSHVI RSVTDLGNVR WDIALSLFVV 240
  241 YLICYFSMWK GIHTSGKVVW FTALFPYVVL GILFIRGVTL PGWQNGIEYY LRPNFEMLKR 300
  301 PSVWQDAATQ VFFSLGPGFG VLMAYSSYND FHNNVYVDAL FTSFINCATS FLSGFVIFSV 360
  361 LGYMSCKSGK PIEAVAQEGP GLVFVVYPEA LSTMPYAPFW SVLFFLMLMT LGLDSSFGGS 420
  421 EAIITGLSDE FPILKKNREV FVGCLFAFYM VIGIAMCTEG GILIMEWLII YGTTWGLLIA 480
  481 VFCEAMVIAY IYGLRQFVHD VKEMMGFRPG NYWKFCWSCA APFILLSMIT SNFINYQALT 540
  541 YQDYTYPTAA NVIGIIFALS GASFIPLVGI YKFVNARGNT ISEKWQRVTM PYRKRPNQTE 600
  601 YIPIPTTQPH SDIML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..615] PSI-BLAST 59.045757 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle